雾化吸入激素治疗老年人支气管哮喘急性发作期的对照试验研究
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4 结论
雾化吸入布地奈德可以改善患者的临床症状及体征，改善患者的肺功能。增大布地奈德混悬液雾化吸入剂量在一定程度上能提高疗效，其6 mg/d与口服泼尼松30 mg/d疗效相当，小于6 mg/d布地奈德混悬液雾化3周不会引起垂体-肾上腺轴的抑制。
[参考文献]
[1]中华医学会呼吸病学分会哮喘学组.支气管哮喘防治指南(支气管哮喘的定义、诊断、治疗和管理方案)[J].中华结核和呼吸杂志,2008,31(3):177-185.
[2]Kyuma O,Takashi H.Analysis of Inhaled Corticosteroid Selection in Patients with Bronchial Asthma Using a Questionnaire Survey-Effects of Age,Gende r,and Disease Severity[J].Allergology International,2009,15(8):365-371.
[3]Adams NP,Jines PW.The dose-response characteristics of inhaled corticosteroids when used to treat asthma: an overview of Cochrane systematic reviews[J].Resir med,2006,100(8):1297-1306.
[4]Masoli M,Weatherall M,Holt S,et al.Systematic review of the dose-response relation of inhaled fluticasone propionate[J].Arch Dis Child,2004, 89(10):902-907.
[5]Mikhak Z.Dose-response studies of fluticasone propionate and budesonide: classification based on asthma severity[J].Allergy Asthma Proc,2006, 27(5):402-411.
[6]Clark DJ,Lipworth BJ.Dose-response of inhaled drugs in asthma An update [J].Clin Pharmacokinet,1997,32(1):58-74.
[7]Murphy K,Noonan M,Silkoff PE,et al.A 12-week,muticenter,randomized,partially blinded,active-controlled,parallel-group study of budesonide inhalation suspension in adolescents and adults with moderate to severe persistent asthma previously receiving inhaled corticosteroids with a metered-dose or dry powder inhaler[J].Clin Ther,2007,29(6):1013-1026.
[8]Suna Buyukozturk S.Acute Phase Reactants in Allgeric Airway Disease[J].TohokuJExp.Med,2004,204(3):209-213.
[9]Dane EDIGER,Funda COKUN,Esra KUNT UZASLAN,et al.Clinical effectiveness of nebulised budesonide in the treatment of acute asthma attacks[J].Tüberkülozve Toraks Dergisi,2006,54(2):128-136.
(收稿日期：2011-06-07)
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