静脉应用盐酸普罗帕酮和胺碘酮治疗阵发性室上性心动过速疗效观察
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[摘要] 目的：比较静脉应用盐酸普罗帕酮和胺碘酮治疗阵发性室上性心动过速的疗效。方法：选择本院2008年1月～2010年6月入院的阵发性室上性心动过速患者65例，将其随机分为盐酸普罗帕酮组35例和胺碘酮组30例，比较两组用药前后的心率、血压、转复时间及转复有效率。结果：盐酸普罗帕酮组和胺碘酮组患者的心率在用药前(184.8±27.5 vs 183.4±28.1)、后(82.7±5.3 vs 84.85±6.7)比较，差异无统计学意义(P>0.05)，但用药前与用药后(184.8±27.5 vs 82.7±5.3)、(183.4±28.1 vs 84.8±6.7)比较，效果显著(P<0.05)；两组的转复时间(12.8±6.7 vs 28.6±11.2)比较，差异有统计学意义(P<0.05)；两组患者用药前后血压(104.5±13.5/72.7±10.3 vs 103.4±15.1/74.8±12.7)、(102.6±9.4/73.5±9.9 vs 106.8±10.5/71.7±9.3)变化不大，差异无统计学意义(P>0.05)，但转复率分别为100%(35/35)、90%(27/30)，差异有统计学意义。结论：盐酸普罗帕酮与胺碘酮治疗阵发性室上性心动过速效果均较好，盐酸普罗帕酮注射液更适合应用于心功能正常或对其耐受性较好的患者，故无器质性心脏病的患者可优先选用。胺碘酮可以应用于治疗伴有器质性心脏病的心律失常。
[关键词] 盐酸普罗帕酮；胺碘酮；阵发性室上性心动过速；疗效观察
[中图分类号] R972[文献标识码]B [文章编号]1674-4721(2011)07(c)-077-03
Efficiay observation of propafenone and amiodarone in treating paroxysmal supraventricular tachycardia
YUAN Yulian, DAI Lihua
Department of Internal Medicine of the Emergency Call, the Second People's Hospital of Liwan District in Guangzhou City, Guangdong Province, Guangzhou 510160, China
[Abstract] Objective: To observe the effects of propafenone and amiodarone in treating paroxysmal supraventricular tachycardia (PSVT). Methods: 65 patients with PSVT were slected in January 2008 to June 2010 and were divided into propafenone group 35 cases and amiodarone group 30 cases, propafenone group were treated with propafenone and amiodarone group were treated with amiodarone. Compared the heart rate, blood pressure and cardioversion time and the conversion efficiency of two groups. Results: The differences of heart rate between propafenone group and amiodarone group before treatment (184.8±27.5 vs 183.4±28.1) and after treatment (82.7±5.3 vs 84.8±6.7) were not significant (P>0.05). But before and after treatment, the propafenone group (184.8±27.5 vs 82.7±5.3) and amiodarone group (183.4±28.1 vs 84.85±6.7) had significant differences (P<0 ......
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