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不同胰岛素给药方法治疗糖尿病的临床效果对比(1)
http://www.100md.com 2018年4月15日 《中国当代医药》 2018年第11期
     [摘要]目的 探究不同胰岛素给药方法治疗糖尿病的临床效果。方法 选取我院2016年6月~2017年8月收治的91例糖尿病患者作為研究对象,根据给药方式分为对照组(42例)和治疗组(49例),对照组患者采取皮下注射胰岛素治疗,治疗组患者采取胰岛素泵输注胰岛素治疗,比较两组患者的临床治疗效果。结果 治疗组患者总有效率为95.92%,高于对照组(83.33%),差异有统计学意义(P<0.05);治疗组患者治疗后空腹血糖水平为(6.23±0.85)mmol/L,低于对照组(7.15±1.23)mmol/L,治疗组患者空腹血糖达标时间短于对照组,平均胰岛素用量低于对照组,差异均有统计学意义(P<0.05);治疗组患者低血糖发生率为2.04%,低于对照组(14.29%),差异有统计学意义(P<0.05)。结论 糖尿病患者采取胰岛素泵治疗方法,可以减少胰岛素用量,疗效高,对患者空腹血糖改善起到显著的作用,利于患者血糖控制,在临床治疗中具有重要的应用价值。

    [关键词]不同胰岛素给药方法;糖尿病;空腹血糖

    [中图分类号] R587.1 [文献标识码] A [文章编号] 1674-4721(2018)4(b)-0047-03

    Clinical effect comparison of different insulin delivery methods on diabetes mellitus

    YU Li-qin

    Department of Endocrinology,Central Hospital of Zibo Mining Group Co.,Ltd.,Shandong Province,Zibo 255120,China

    [Abstract]Objective To explore the clinical effect of different insulin delivery methods on diabetes mellitus (DM).Methods 91 cases DM patients from June 2016 to August 2017 were selected as research objects in our hospital.They were divided into control group (n=42) and treatment group (n=49) according to the mode of administration.In the control group,subcutaneous insulin therapy was used,while in the treatment group,insulin pump infusion therapy was adopted.The clinical efficacy of the two groups was compared.Results The total effectiveness rate of the treatment group was 95.92%,significantly higher than that in the control group accounting for 83.33%,with a significant difference(P<0.05).The fasting blood glucose level in the treatment group after therapy was (6.23±0.85) mmol/L,lower than that in the control group (7.15±1.23) mmol/L.The time of fasting blood glucose meeting the standard in the treatment group was shorter,and the average insulin dose was lowerer compared with those in the control group,with statistical differences(P<0.05).The incidence of hypoglycemia was 2.04%,lower than that in the control group accounting for 14.29%,with a statistical difference (P<0.05).Conclusion Insulin treatment in DM patients,insulin pump therapy can reduce the insulin dose in high effect,greatly improve the fasting blood glucose,and benefit patient′s glycemic control,and play an important application value in clinical treatment.

    [Key words]Different insulin delivery methods;Diabetes mellitus;Fasting blood glucose

    糖尿病是临床常见的一种慢性代谢性疾病,以血糖升高为主要特征。相关研究指出,大部分糖尿病患者血糖升高均由胰岛素分泌缺陷、胰岛素生物作用损伤导致,患者长期血糖处于升高状态,易造成多器官受到严重的损伤,进一步造成器官功能障碍,对患者健康造成严重的威胁[1]。诱发糖尿病发生的因素很多,如遗传因素、环境因素等。在临床糖尿病治疗中,以药物治疗为首选治疗方法,胰岛素是糖尿病最常用的治疗药物之一。为探究糖尿病应用不同胰岛素给药方法治疗的临床疗效差异性,本研究回顾性分析我院收治的91例糖尿病患者资料,并将其整理分组观察,现报道如下。, http://www.100md.com(于立芹)
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