米索前列醇与COOK子宫颈扩张球囊在妊娠晚期促宫颈成熟中的应用效果比较(1)
[摘要]目的 比较米索前列醇和COOK子宫颈扩张球囊在妊娠晚期促宫颈成熟中的应用效果。方法 选取2016年1月～2019年7月在我院有引产指征且宫颈评分不成熟的晚期妊娠孕妇90例作为研究对象，按抽签随机法分为米索前列醇组(A组)40例，COOK球囊组(B组)50例。比较两组治疗前后宫颈评分、分娩结局、并发症发生率及新生儿情况。结果 治疗后两组的宫颈评分高于治疗前，差异有统计学意义(P<0.05)。B组促宫颈成熟有效率高于A组(P<0.05)。A组宫缩过频、胎儿窘迫发生率高于B组，差异均有统计学意义(P<0.05)，两组剖宫产率、产后出血率、新生儿窒息率比较，差异无统计学意义(P>0.05)。结论 COOK子宫颈扩张球囊、米索前列醇均可明显改善宫颈成熟度，但COOK子宫颈扩张球囊效果更佳，使用安全性更高，值得临床推广应用。
[关键词]米索前列醇;子宫颈扩张球囊;促宫颈成熟;引产;晚期妊娠
[中图分类号] R719.3 [文献标识码] A [文章编号] 1674-4721(2020)5(a)-0080-03
Application effect comparison of Misoprostol and COOK cervical dilatation balloon in promoting cervical ripening in late pregnancy
JIANG Yan-yan MIAO Li-lin
Department of Obstetrics， Houjie Hospital of Dongguan City in Guangdong Province， Dongguan 523000， China
[Abstract] Objective To compare the effect of Misoprostol and cook cervical dilatation balloon in promoting cervical ripening in late pregnancy. Methods Ninety late pregnant women with indications of induced labor and immature cervix from January 2016 to July 2019 in our hospital were selected as research objects. They were randomly divided into 40 cases of Misoprostol group (group A)， 50 cases of COOK balloon group (group B) by drawing. The cervical score before and after treatment， delivery outcome， complications and neonatal condition of pregnant women were compared between two groups. Results The cervical score of the two groups after treatment were higher than those before treatment， the differences were statistically significant (P<0.05). The effective rate of promoting cervical maturation in group B was higher than that in group A (P<0.05). The incidence of uterine contraction overfrequency and fetal distress in group A were higher than that in group B (P<0.05). There were no significant differences in cesarean section rate， postpartum hemorrhage rate and neonatal asphyxia between the two groups (P>0.05). Conclusion COOK cervical dilatation balloon and Misoprostol can significantly improve cervical ripening， but COOK cervical dilatation balloon is more safe and worthy of clinical application.
[Key words] Misoprostol; Cervical dilatation balloon; Cervical ripening; Labor induction; Late pregnancy
自然分娩是一种正常生理现象，有利于产妇恢复及新生儿健康。妊娠晚期因各种因素需提前终止妊娠，提高自然分娩率，降低剖宫产率成为产科医生必须做的事情。妊娠晚期通过药物或机械等手段软化宫颈，使产程发动，达到自然分娩，是产科处理高危妊娠常用的手段之一。子宫颈成熟程度是引产成功的关键。常用的促宫颈成熟方法有普贝生、米索前列醇、缩宫素、COOK子宫颈扩张球囊、Foley尿管等[1]。本研究比较米索前列醇与COOK子宫颈擴张球囊两种促宫颈成熟方法的应用效果，为临床工作提供参考，现报道如下。, 百拇医药(姜艳艳 缪丽琳)
[关键词]米索前列醇;子宫颈扩张球囊;促宫颈成熟;引产;晚期妊娠
[中图分类号] R719.3 [文献标识码] A [文章编号] 1674-4721(2020)5(a)-0080-03
Application effect comparison of Misoprostol and COOK cervical dilatation balloon in promoting cervical ripening in late pregnancy
JIANG Yan-yan MIAO Li-lin
Department of Obstetrics， Houjie Hospital of Dongguan City in Guangdong Province， Dongguan 523000， China
[Abstract] Objective To compare the effect of Misoprostol and cook cervical dilatation balloon in promoting cervical ripening in late pregnancy. Methods Ninety late pregnant women with indications of induced labor and immature cervix from January 2016 to July 2019 in our hospital were selected as research objects. They were randomly divided into 40 cases of Misoprostol group (group A)， 50 cases of COOK balloon group (group B) by drawing. The cervical score before and after treatment， delivery outcome， complications and neonatal condition of pregnant women were compared between two groups. Results The cervical score of the two groups after treatment were higher than those before treatment， the differences were statistically significant (P<0.05). The effective rate of promoting cervical maturation in group B was higher than that in group A (P<0.05). The incidence of uterine contraction overfrequency and fetal distress in group A were higher than that in group B (P<0.05). There were no significant differences in cesarean section rate， postpartum hemorrhage rate and neonatal asphyxia between the two groups (P>0.05). Conclusion COOK cervical dilatation balloon and Misoprostol can significantly improve cervical ripening， but COOK cervical dilatation balloon is more safe and worthy of clinical application.
[Key words] Misoprostol; Cervical dilatation balloon; Cervical ripening; Labor induction; Late pregnancy
自然分娩是一种正常生理现象，有利于产妇恢复及新生儿健康。妊娠晚期因各种因素需提前终止妊娠，提高自然分娩率，降低剖宫产率成为产科医生必须做的事情。妊娠晚期通过药物或机械等手段软化宫颈，使产程发动，达到自然分娩，是产科处理高危妊娠常用的手段之一。子宫颈成熟程度是引产成功的关键。常用的促宫颈成熟方法有普贝生、米索前列醇、缩宫素、COOK子宫颈扩张球囊、Foley尿管等[1]。本研究比较米索前列醇与COOK子宫颈擴张球囊两种促宫颈成熟方法的应用效果，为临床工作提供参考，现报道如下。, 百拇医药(姜艳艳 缪丽琳)
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