更昔洛韦治疗小儿手足口病90例临床对照研究(1)
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【摘要】 目的 观察更昔洛韦治疗小儿手足口病的临床疗效。方法 将180例手足口病患儿随机分为治疗组和对照组，各90例。两组均给予口服维生素C、补液、对症等常规治疗，同时治疗组给予更昔洛韦5 mg/(kg•d)加入液体中静脉滴注，对照组给予利巴韦林10～15 mg/(kg•d)加入液体中静脉滴注，观察两组的临床症状、体征及不良反应。结果 治疗组临床症状及体征均较对照组消失早(P<0.05)；治疗组总有效率为96.7%，对照组总有效率为82.2%(P<0.05)；两组均未见明显不良反应。结论 更昔洛韦治疗小儿手足口病具有疗效显著、疗程缩短的特点，且无不良反应。
【关键词】 更昔洛韦； 利巴韦林； 手足口病； 小儿
Clinical control study on clinical effect of ganciclovir on 90 children with hand-foot-mouth disease CHEN Yi-hui,YANG Wei-bo, LI Yun-bo.The First Affiliated Hospital of Kunming Medical University,Kunming 650032，China
【Abstract】 Objective To observe the curative effects of ganciclovir on children with hand-feet-mouth disease(HFMD).Methods One hundred eighty children with HFMD were randomly divided into two groups treated with conventional therapy such as vitamin C, fluid and symptomatic treatment ......
【摘要】 目的 观察更昔洛韦治疗小儿手足口病的临床疗效。方法 将180例手足口病患儿随机分为治疗组和对照组，各90例。两组均给予口服维生素C、补液、对症等常规治疗，同时治疗组给予更昔洛韦5 mg/(kg•d)加入液体中静脉滴注，对照组给予利巴韦林10～15 mg/(kg•d)加入液体中静脉滴注，观察两组的临床症状、体征及不良反应。结果 治疗组临床症状及体征均较对照组消失早(P<0.05)；治疗组总有效率为96.7%，对照组总有效率为82.2%(P<0.05)；两组均未见明显不良反应。结论 更昔洛韦治疗小儿手足口病具有疗效显著、疗程缩短的特点，且无不良反应。
【关键词】 更昔洛韦； 利巴韦林； 手足口病； 小儿
Clinical control study on clinical effect of ganciclovir on 90 children with hand-foot-mouth disease CHEN Yi-hui,YANG Wei-bo, LI Yun-bo.The First Affiliated Hospital of Kunming Medical University,Kunming 650032，China
【Abstract】 Objective To observe the curative effects of ganciclovir on children with hand-feet-mouth disease(HFMD).Methods One hundred eighty children with HFMD were randomly divided into two groups treated with conventional therapy such as vitamin C, fluid and symptomatic treatment ......
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