Snail与结直肠癌关系的研究进展(1)
作者单位：524001 广东医学院附属医院
通讯作者：王亮
【摘要】 结直肠癌是常见的消化道恶性肿瘤，在治疗上主要依靠手术切除以及放射、化疗等综合治疗。但其术后5年生存率仅50%左右，目前尚无早期有效的检测手段来明确肿瘤的分期及有无转移，也是患者复发和死亡的主要原因。Snail是近年发现的锌指转录因子，其基因的表达水平与肿瘤的浸润转移呈明显的正相关。因此，Snail可以作为肿瘤早期诊断和预后的分子标志物。为结直肠癌治疗提供新方向。本文综述该因子与结直肠癌关系的研究进展。
【关键词】 结直肠癌； 肿瘤； Snail
Progess about relationship between Snalil and colorectal cancer WANG Liang,XU Qing-wen.Affilicated Hospital of Guangdong Medical College,Zhanjiang 524001,China
【Abstract】 Colorectal cancer is a common gastrointestinal m alignancy, it's treatment rely includes the surgical resection, radiation and chemotherapy treatment etc. But the postoperative 5-year survival rate only has about 50 percent for lacking of early detection means to clear the effective and presence of tumor stages, but also the main causes of patients relapse and metastasis. Snail is found in recent years, the zinc finger transcription factor gene expression level and tumor metastasis is obviously positive correlation. Therefore, it can serve as tumor early diagnosis and prognosis of the molecular markers. For colorectal cancer treatments with new direction. This paper reviewed the factor and the research progress of colorectal cancer relationship. ......
您现在查看是摘要页，全文长 5106 字符。
通讯作者：王亮
【摘要】 结直肠癌是常见的消化道恶性肿瘤，在治疗上主要依靠手术切除以及放射、化疗等综合治疗。但其术后5年生存率仅50%左右，目前尚无早期有效的检测手段来明确肿瘤的分期及有无转移，也是患者复发和死亡的主要原因。Snail是近年发现的锌指转录因子，其基因的表达水平与肿瘤的浸润转移呈明显的正相关。因此，Snail可以作为肿瘤早期诊断和预后的分子标志物。为结直肠癌治疗提供新方向。本文综述该因子与结直肠癌关系的研究进展。
【关键词】 结直肠癌； 肿瘤； Snail
Progess about relationship between Snalil and colorectal cancer WANG Liang,XU Qing-wen.Affilicated Hospital of Guangdong Medical College,Zhanjiang 524001,China
【Abstract】 Colorectal cancer is a common gastrointestinal m alignancy, it's treatment rely includes the surgical resection, radiation and chemotherapy treatment etc. But the postoperative 5-year survival rate only has about 50 percent for lacking of early detection means to clear the effective and presence of tumor stages, but also the main causes of patients relapse and metastasis. Snail is found in recent years, the zinc finger transcription factor gene expression level and tumor metastasis is obviously positive correlation. Therefore, it can serve as tumor early diagnosis and prognosis of the molecular markers. For colorectal cancer treatments with new direction. This paper reviewed the factor and the research progress of colorectal cancer relationship. ......
您现在查看是摘要页，全文长 5106 字符。