丹红注射液对颈动脉狭窄支架成形术后C反应蛋白的影响(1)
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【摘要】 目的:探讨丹红注射液对颈动脉狭窄支架成形术后C反应蛋白的影响。方法:选择颈动脉狭窄患者80例,随机分为治疗组40例和对照组40例,两组都采用支架成形术,在此基础上治疗组加用丹红注射液治疗。结果:经过治疗后,治疗组与对照组的有效率分别为90.0%和62.5%,两组对比差异有统计学意义(P<0.05)。经过治疗,治疗组CRP的下降幅度比大于对照组(P<0.05)。结论:丹红注射液应用于颈动脉狭窄支架成形术能有效提高治疗疗效,降低C反应蛋白水平,值得推广应用。
【关键词】 丹红注射液; 颈动脉狭窄; 支架成形术; C反应蛋白
The Effect of DanHong Injection on C-reactive Protein after Carotid Angioplasty and Stenting/WANG Song-lin.//Medical Innovation of China,2012,9(28):016-017
【Abstract】 Objective:To investigate the effect of DanHong injection on C-reactive protein after Carotid Angioplasty and Stenting.Method:80 cases of carotid artery stenosis were randomly divided into treatment group and control group.The two groups were treated by angioplasty and stenting.On the basis of that,the treatment group was additional treated with DanHong injection.Result:The efficiency of the treatment group and control group were 90.0% and 62.5%(P<0.05),respectively.A decrease of CRP in the treatment group were more than control group(P<0.05).Conclusion:The administration of DanHong injection in the carotid artery stenosis stenting can effectively improve the therapeutic efficacy and reduce the level of C-reactive protein,and it should be widely applied in clinic.
【Key words】 DanHong injection; Carotid stenosis; Stenting; C-reactive protein
First-author’s address:The Central Hospital of Xuchang,Xuchang 461000,China
doi:10.3969/j.issn.1674-4985.2012.28.007
颈动脉狭窄多是由于颈动脉的粥样斑块导致的颈动脉管腔的狭窄,其发病率较高,在60岁以上人群中患颈动脉狭窄者约占9%,其是引起脑缺血发作和卒中的重要原因[1]。约25%的缺血性脑卒中的发生与颈动脉粥样硬化性狭窄有关[2]。在我国,随着人民生活水平的提高、生活方式和食物来源构成比的变化,颈动脉狭窄发病率呈逐年上升趋势,且发病日趋年轻化[3]。同时颈动脉发生与C反应蛋白(CRP)含量的变化有密切相关性。而丹红注射液能够降低CRP水平,临床上多用于颈动脉狭窄的治疗。为此,本文具体探讨了丹红注射液对颈动脉狭窄支架成形术后C反应蛋白的影响,现报告如下。
1 资料与方法
1.1 一般资料 选择2009年2月-2011年10月笔者所在医院收治的颈动脉狭窄患者80例,入选本研究的标准为:(1)符合颈动脉狭窄的诊断标准;(2)颈动脉狭窄程度≥50%,适应于支架成形术;(3)征得患者及其家属同意;(4)排除心肝颈等各项功能等异常者 ......
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