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依那普利联合倍他乐克对高血压的疗效观察(1)
http://www.100md.com 2015年6月25日 《中国医学创新》 2015年第18期
     【摘要】 目的:探讨依那普利联合倍他乐克治疗高血压的临床疗效。方法:收集近两年在本院接受治疗的高血压患者作为本次的研究对象,将患者分为观察组和对照组,每组49例,对照组患者采用硝苯地平缓释片治疗,观察组患者采用依那普利联合倍他乐克治疗,对比分析两组患者的临床疗效。结果:观察组患者的治疗总有效率明显高于对照组,比较差异有统计学意义(P<0.05);观察组与对照组患者的不良反应发生率分别为2.0%、10.2%,两组患者比较差异有统计学意义(P<0.05)。两组患者治疗前血压比较差异无统计学意义(P>0.05),治疗后两组患者均有所改善,但观察组患者的改善情况明显优于对照组(P<0.05)。结论:采用依那普利联合倍他乐克治疗高血压可有效提高治疗效果,改善患者血压情况,且安全性较高,应推广应用。

    【关键词】 依那普利; 倍他乐克; 高血压

    Efficacy Observation of Enalapril Combined with Betaloc in the Treatment of Hypertension/WANG Dong-jiang,XU Ping.//Medical Innovation of China,2015,12(18):041-043
, http://www.100md.com
    【Abstract】 Objective:To investigate the clinical efficacy of Enalapril combined with Betaloc in the treatment of hypertension.Method:98 cases of hypertension patients in our hospital were selected as the study objects,they were randomly divided into the observation group and the control group,49 cases in each group.Patients in the control group were given extended release nifedipine tablets treatment,the observation group was treated with Enalapril and Betaloc.The clinical efficacy of the two groups were analyzed.Result:The total effective rate of the observation group was significantly higher than that of the control group(P<0.05).The adverse reactions rate of the observation group was significantly lower than that of the control group(P<0.05).The blood pressure of the two groups had no significant difference before treatment(P>0.05).After the treatment,the situation of the two groups were both improved,but the improvement of the observation group was much better than that of the control group(P<0.05).Conclusion:Using Enalapril combined with Betaloc in the treatment of hypertension can be effectively and improve patients’ blood pressure.It has high security and should be popularized and applied.
, 百拇医药
    【Key words】 Enalapril; Betaloc; Hypertension

    First-author’s address:Cadre Sanatorium of Guangzhou City,Guangzhou 510530,China

    doi:10.3969/j.issn.1674-4985.2015.18.015

    高血压是临床上的常见病、多发病,该病具有较高的发病率,且该病是多种心脑血管疾病的基础病及重要危险因素,其并发症具有较高的致残率,严重时甚至会导致患者死亡,已成为威胁人类健康的一大杀手,严重威胁着患者的身体健康及生命安全。因此,及时采取有效的措施进行治疗,就显得至关重要。药物治疗是目前临床上治疗高血压的常用药物。依那普利与倍他乐克联合使用在高血压患者的治疗中取得了较好的效果。本次研究为探讨依那普利联合倍他乐克治疗高血压的临床疗效,提高高血压的治疗效果,本院采用硝苯地平缓释片与依那普利联合倍他乐克两种方式对98例高血压患者进行治疗,效果显著,具体报告如下。

    1 资料与方法

    1.1 一般资料 选取2012年6月-2014年6月在本院接受治疗的98例高血压患者作为本次的研究对象,采用随机数字表法抽取49例作为观察组,其中男28例,女21例,年龄45~75岁,平均(54.3±2.8)岁;病程1个月~2年,平均(12.6±0.5)个月;另49例患者作为对照组,其中男29例,女20例,年龄42~76岁,平均(55.9±3.1)岁;病程2个月~2年,平均 (13.2±0.6)个月;两组患者年龄、性别、病程等临床资料经均衡性检验差异均无统计学意义(P>0.05),具有可比性。, http://www.100md.com(王东江 徐萍)
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