老年患者无痛胃镜术中应用地佐辛与丙泊酚的疗效研究(1)
【摘要】 目的：探究老年患者无痛胃镜术中应用地佐辛与丙泊酚的疗效。方法：选取2012年6月-2014年6月在本院接受治疗的95例行无痛胃镜术的老年患者作为本次研究试验对象，观察组采用地佐辛和丙泊酚进行麻醉，对照组采用盐酸瑞芬太尼和丙泊酚进行麻醉，观察比较两组患者的麻醉效果、各项体征指标和不良反应发生情况。结果：T2时，观察组患者的MAP和HR较T1时均明显降低，观察组的MAP明显高于对照组，差异均有统计学意义(P<0.05)，同时期对照组患者的MAP和SpO2较T1时均明显降低，差异均有统计学意义(P<0.05)；T3时，观察组患者的HR明显低于观察组，而SpO2值稍高于对照组，比较差异均有统计学意义(P<0.05)。观察组患者平均麻醉起效、清醒时间均明显短于对照组，VAS评分明显低于对照组，总不良反应发生率10.42%明显低于对照组的38.30%，比较差异均有统计学意义(P<0.05)。结论：老年行无痛胃镜手术患者使用地佐辛联合丙泊酚的麻醉疗效较好，术中麻醉起效快，疼痛小，有利于胃镜手术的实施，麻醉清醒时间短，术后患者不良反应少，安全性高，值得广泛推荐使用于临床当中。
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【关键词】 老年无痛胃镜术； 地佐辛； 丙泊酚； 疗效
Research on the Application Effect of Dezocine Combined with Propofol in Elderly Patients with Painless Gastroscopy/XU Wei，ZHAN Sheng-fu.//Medical Innovation of China，2015，12(26)：133-135
【Abstract】 Objective：To study the application efficacy of Dezocine combined with Propofol in elderly patients with painless gastroscopy.Method：95 elderly patients with painless gastroscopy admitted to our hospital from June 2012 to June 2014 were selected as research objects in the study，the observation group was given Dezocine combined with Propofol for anesthesia，the control group was given Remifentanil Hydrochloride combined with Propofol for anesthesia.The anesthetic effect，the signs of indicators and adverse reactions between the two groups were observed and compared.Result：Compared with T1 time point，the MAP and HR values of the observation group at T2 time point were significantly lower，the MAP of the observation group was significantly higher than the control group，the differences were statistically significant(P<0.05)，while the MAP and SpO2 of the control group were significantly lower，the differences were statistically significant(P<0.05).At T3 time point，the HR of the observation group was significantly lower than the control group，and the SpO2 value was slightly higher than the control group，the differences were statistically significant(P<0.05).The average onset time of anesthesia，anesthesia awake time in the observation group were significantly shorter than the control group，the VAS score was significantly lower than the control group，the total incidence of adverse reactions in the observation group was 10.42%，which was significantly lower than 38.30% in the control group，the differences were statistically significant(P<0.05).Conclusion：The anesthetic effect of Dezocine combined with Propofol in elderly patients with painless gastroscopy is better，intraoperative anesthetic effect quickly，with little pain，is conducive to the implementation of endoscopic surgery，shorter anesthesia awake time，less postoperative adverse reactions，with high safety，is recommended to be widely used in clinic., 百拇医药(徐韦 占胜福)
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【关键词】 老年无痛胃镜术； 地佐辛； 丙泊酚； 疗效
Research on the Application Effect of Dezocine Combined with Propofol in Elderly Patients with Painless Gastroscopy/XU Wei，ZHAN Sheng-fu.//Medical Innovation of China，2015，12(26)：133-135
【Abstract】 Objective：To study the application efficacy of Dezocine combined with Propofol in elderly patients with painless gastroscopy.Method：95 elderly patients with painless gastroscopy admitted to our hospital from June 2012 to June 2014 were selected as research objects in the study，the observation group was given Dezocine combined with Propofol for anesthesia，the control group was given Remifentanil Hydrochloride combined with Propofol for anesthesia.The anesthetic effect，the signs of indicators and adverse reactions between the two groups were observed and compared.Result：Compared with T1 time point，the MAP and HR values of the observation group at T2 time point were significantly lower，the MAP of the observation group was significantly higher than the control group，the differences were statistically significant(P<0.05)，while the MAP and SpO2 of the control group were significantly lower，the differences were statistically significant(P<0.05).At T3 time point，the HR of the observation group was significantly lower than the control group，and the SpO2 value was slightly higher than the control group，the differences were statistically significant(P<0.05).The average onset time of anesthesia，anesthesia awake time in the observation group were significantly shorter than the control group，the VAS score was significantly lower than the control group，the total incidence of adverse reactions in the observation group was 10.42%，which was significantly lower than 38.30% in the control group，the differences were statistically significant(P<0.05).Conclusion：The anesthetic effect of Dezocine combined with Propofol in elderly patients with painless gastroscopy is better，intraoperative anesthetic effect quickly，with little pain，is conducive to the implementation of endoscopic surgery，shorter anesthesia awake time，less postoperative adverse reactions，with high safety，is recommended to be widely used in clinic., 百拇医药(徐韦 占胜福)