中西医结合对支原体肺炎患儿炎性状态及治疗效果的影响研究(1)
【摘要】 目的：探讨中西医结合对支原体肺炎患儿炎性状态和治疗效果的影响研究。方法：将本院2014年1-12月收治的100例支原体肺炎患儿随机分为对照组与观察组，每组各50例，对照组给予阿奇霉素治疗及对症治疗，观察组在对照组基础上给予喜炎平，治疗7 d后比较两组的治疗效果及炎性水平。结果：治疗7 d后，对照组总有效率68.0%，观察组总有效率98.0%，两组比较差异有统计学意义(P<0.05)。两组治疗前的血清CPR、IL-6、TNF-α水平比较差异均无统计学意义(P>0.05)；治疗后的血清各水平比较差异均有统计学意义(P<0.05)。两组治疗前轻度及中度的CPR、IL-6、TNF-α水平比较差异均无统计学意义(P>0.05)，两组治疗后轻度及中度的各水平比较差异均有统计学意义(P<0.05)。结论：中西医结合治疗小儿支原体肺炎疗效显著，明显改善患儿炎症状态水平，值得临床推广应用。
【关键词】 小儿支原体肺炎； 喜炎平； 阿奇霉素
Observation of Inflammatory States and Effect on Children with Mycoplasma Pneumonia in Combination of Chinese and Western medicine/YU Zhi-xin，XIE Xiao-qin.//Medical Innovation of China，2015，12(34)：099-102
, 百拇医药
【Abstract】 Objective ：To investigate the inflammatory states and effect of combined Chinese and western medicine in children with mycoplasma pneumonia.Method：100 Children with mycoplasma pneumonia in our hospital were selected from January to December 2014，they were randomly divided into control group and observation group， 50 cases in each group.The control group was given azithromycin and symptomatic treatment， the observation group was used Xiyanping on the base of control group.After 7 days treatment，the effect and inflammatory level of two groups were compared.Result： after 7 days treatment， the total efficiency of control group was 68.0%， the total efficiency of observation group was 98.0%，the difference was statistically significant (P<0.05).Compared the levels of CPR，IL-6 and TNF-α of two groups before treatment，the difference was statistically significant(P<0.05)；after treatment，compared the levels of two groups，the differences were statistically significant(P<0.05).Before treatment，compared the levels of CPR， IL-6 and TNF-α of two groups with mild and moderate，the differences were not statistically significant(P>0.05)；after treatment， compared two groups of that， the differences were statistically significant(P<0.05).Conclusion：Combination of Chinese and western medicine in children with mycoplasma pneumonia can significantly improve the efficacy and the level of inflammation，it is worthy of clinical application.
, 百拇医药
【Key words】 Mycoplasma Pneumonia； Xiyanping； azithromycin
First-author’s address：Maternity and Child Care Hospital of Pingxiang，Pingxiang 337000，China
doi：10.3969/j.issn.1674-4985.2015.34.031
支原体肺炎(Mycoplasmal pneumonia，MPP)又称原发性非典型肺炎(Primary atypical，pneumonia)，是支原体(MP)感染引起的肺部急性炎症，是学龄儿童及青年常见的一种肺炎，婴幼儿也不少见[1-2]。小儿MP肺炎的治疗与一般肺炎的治疗原则基本相同，采取综合治疗措施，包括一般治疗、对症治疗、抗生素的应用、肾上腺皮质激素、以及肺外并发症的治疗等5个方面[3-4]。研究发现，小儿支原体肺炎的发病及治疗过程中机体的炎性指标会随着病情的发生发展随之变化，这种变化可有效地反映治疗干预方案的有效性，进而影响治疗效果。笔者对本院2014年1-12月住院的100例患儿进行追踪研究，应用中西医结合的方法进行治疗，观察其对支原体肺炎患儿炎性状态和治疗效果的影响，现将结果汇报如下。, http://www.100md.com(虞致新 谢小琴)
【关键词】 小儿支原体肺炎； 喜炎平； 阿奇霉素
Observation of Inflammatory States and Effect on Children with Mycoplasma Pneumonia in Combination of Chinese and Western medicine/YU Zhi-xin，XIE Xiao-qin.//Medical Innovation of China，2015，12(34)：099-102
, 百拇医药
【Abstract】 Objective ：To investigate the inflammatory states and effect of combined Chinese and western medicine in children with mycoplasma pneumonia.Method：100 Children with mycoplasma pneumonia in our hospital were selected from January to December 2014，they were randomly divided into control group and observation group， 50 cases in each group.The control group was given azithromycin and symptomatic treatment， the observation group was used Xiyanping on the base of control group.After 7 days treatment，the effect and inflammatory level of two groups were compared.Result： after 7 days treatment， the total efficiency of control group was 68.0%， the total efficiency of observation group was 98.0%，the difference was statistically significant (P<0.05).Compared the levels of CPR，IL-6 and TNF-α of two groups before treatment，the difference was statistically significant(P<0.05)；after treatment，compared the levels of two groups，the differences were statistically significant(P<0.05).Before treatment，compared the levels of CPR， IL-6 and TNF-α of two groups with mild and moderate，the differences were not statistically significant(P>0.05)；after treatment， compared two groups of that， the differences were statistically significant(P<0.05).Conclusion：Combination of Chinese and western medicine in children with mycoplasma pneumonia can significantly improve the efficacy and the level of inflammation，it is worthy of clinical application.
, 百拇医药
【Key words】 Mycoplasma Pneumonia； Xiyanping； azithromycin
First-author’s address：Maternity and Child Care Hospital of Pingxiang，Pingxiang 337000，China
doi：10.3969/j.issn.1674-4985.2015.34.031
支原体肺炎(Mycoplasmal pneumonia，MPP)又称原发性非典型肺炎(Primary atypical，pneumonia)，是支原体(MP)感染引起的肺部急性炎症，是学龄儿童及青年常见的一种肺炎，婴幼儿也不少见[1-2]。小儿MP肺炎的治疗与一般肺炎的治疗原则基本相同，采取综合治疗措施，包括一般治疗、对症治疗、抗生素的应用、肾上腺皮质激素、以及肺外并发症的治疗等5个方面[3-4]。研究发现，小儿支原体肺炎的发病及治疗过程中机体的炎性指标会随着病情的发生发展随之变化，这种变化可有效地反映治疗干预方案的有效性，进而影响治疗效果。笔者对本院2014年1-12月住院的100例患儿进行追踪研究，应用中西医结合的方法进行治疗，观察其对支原体肺炎患儿炎性状态和治疗效果的影响，现将结果汇报如下。, http://www.100md.com(虞致新 谢小琴)