动态无创PAP测定在重症肺炎合并呼吸衰竭患儿中的应用价值分析(1)
【摘要】 目的：探析动态无创肺动脉压力(PAP)测定在重症肺炎合并呼吸衰竭患儿中的应用价值。方法：选取2012年2月-2014年10月本院收治的重症肺炎合并呼吸衰竭患儿55例作为研究对象，根据是否肺动脉高压(PAH)，将其分为PAP正常组19例和PAH组36例，均实施综合治疗，对比两组患儿的机械通气使用情况以及治疗转归情况。另对PAH组加用米力农注射液治疗，对比其治疗前后PAP以及心功能指标的变化。结果：PAH组机械通气率83.33%明显高于PAP正常组的36.84%，机械通气时间明显长于PAP正常组，差异均有统计学意义(P<0.05)。PAH组患儿治疗后的PAP测定值为(49.08±4.71)mm Hg，明显低于治疗前的(58.31±5.42)mm Hg，差异有统计学意义(P<0.05)。而PAH组治疗前后的CI、LVEF和E/A值比较差异均无统计学意义(P>0.05)。PAH组的好转出院率为80.56%、死亡率为19.44%，PAP正常组19例患儿均好转出院，两组比较差异有统计学意义( 字2=4.233，P=0.040)。结论：动态无创PAP测定用于重症肺炎合并呼吸衰竭患儿能为预后判断和病情评估提供依据，且米力农用药能有效降低PAP，值得临床应用。
, 百拇医药
【关键词】 超声心电图； 肺动脉压力； 重症肺炎； 呼吸衰竭； 儿童
【Abstract】 Objective：To investigate the application value of dynamic noninvasive pulmonary arterial pressure(PAP) in the severe pneumonia complicated with respiratory failure.Method：55 severe pneumonia children complicated with respiratory failure admitted to our hospital from February 2012 to October 2014 were selected as the research objects.And according to whether the pulmonary arterial hypertension(PAH)，all children were divided into the normal PAP group for 19 cases and the PAH group for 36 cases，they were given comprehensive treatment.The mechanical ventilation use and treatment outcome between the two groups were compared.The PAH group was treated with Milrinone Injection for treatment on the basis of comprehensive treatment，the PAP and the change of cardiac function indexes before and after treatment were compared.Result：The mechanical ventilation rate of the PAH group was (83.33%) significantly higher than 36.84% of the normal PAP group，the mechanical ventilation time of the PAH group was significantly longer than the normal PAP group，the differences were statistically significant(P<0.05).The PAP determination of PAH group after treatment was (49.08±4.71)mm Hg，which was significantly lower than (58.31±5.42)mm Hg of before treatment，the difference was statistically significant(P<0.05)，and there were no statistically significant differences in the CI，LVEF and E/A before and after treatment(P>0.05).The improved discharge rate and mortality rate of the PAH group were 80.56% and 19.44% respectively，19 children of the normal PAP group were cured and discharged from hospital，the difference was statistically significant( 字2=4.233，P=0.040).Conclusion：Dynamic a PAP test for severe pneumonia complicated with respiratory failure children can provide the basis for the prognosis judgment and the severity assessment，and Milrinone medicine can effectively reduce the PAP，is worthy of clinical application., 百拇医药(俞江)
, 百拇医药
【关键词】 超声心电图； 肺动脉压力； 重症肺炎； 呼吸衰竭； 儿童
【Abstract】 Objective：To investigate the application value of dynamic noninvasive pulmonary arterial pressure(PAP) in the severe pneumonia complicated with respiratory failure.Method：55 severe pneumonia children complicated with respiratory failure admitted to our hospital from February 2012 to October 2014 were selected as the research objects.And according to whether the pulmonary arterial hypertension(PAH)，all children were divided into the normal PAP group for 19 cases and the PAH group for 36 cases，they were given comprehensive treatment.The mechanical ventilation use and treatment outcome between the two groups were compared.The PAH group was treated with Milrinone Injection for treatment on the basis of comprehensive treatment，the PAP and the change of cardiac function indexes before and after treatment were compared.Result：The mechanical ventilation rate of the PAH group was (83.33%) significantly higher than 36.84% of the normal PAP group，the mechanical ventilation time of the PAH group was significantly longer than the normal PAP group，the differences were statistically significant(P<0.05).The PAP determination of PAH group after treatment was (49.08±4.71)mm Hg，which was significantly lower than (58.31±5.42)mm Hg of before treatment，the difference was statistically significant(P<0.05)，and there were no statistically significant differences in the CI，LVEF and E/A before and after treatment(P>0.05).The improved discharge rate and mortality rate of the PAH group were 80.56% and 19.44% respectively，19 children of the normal PAP group were cured and discharged from hospital，the difference was statistically significant( 字2=4.233，P=0.040).Conclusion：Dynamic a PAP test for severe pneumonia complicated with respiratory failure children can provide the basis for the prognosis judgment and the severity assessment，and Milrinone medicine can effectively reduce the PAP，is worthy of clinical application., 百拇医药(俞江)