柳州市人群血尿酸水平与骨密度之间的关系(1)
【摘要】 目的：研究柳州市人群血尿酸水平与骨密度间的关系。方法：对柳州市2010年12月-2014年12月进行体检的2150例居民进行回顾性分析，观察居民血尿酸水平与骨密度间的关系。结果：正常血尿酸水平者L1-4部位骨密度显著低于高尿酸水平者，差异有统计学意义(P<0.05)。1050例男性体检者中，正常骨量者178例，平均血尿酸水平为(359.12±42.11)μmol/L；骨量减少者539例，平均血尿酸水平为(331.26±54.25)μmol/L；骨质疏松者333例，平均血尿酸水平为(421.25±32.25)μmol/L，正常骨量体检者的血尿酸水平明显低于骨质疏松患者的血尿酸水平，正常骨量者血尿酸水平高于骨量减少者，比较差异均有统计学意义(F=1161.43，P<0.05)。1100例女性体检者中，正常骨量者197例，平均血尿酸水平为(298.11±62.32)μmol/L；骨量减少者592例，平均血尿酸水平为(281.12±36.52)μmol/L；骨质疏松者311例，平均血尿酸水平为(365.21±85.21)μmol/L，正常骨量者的血尿酸水平也明显低于骨质疏松患者，差异有统计学意义(F=1755.00，P<0.05)；而正常骨量者与骨量减少者的血尿酸水平比较，差异无统计学意义(P>0.05)。结论：机体血尿酸的水平与骨密度密切相关，维持一定的血尿酸水平可预防骨量的丢失，但尿酸水平过高则会导致骨密度值降低，高尿酸血症与骨质疏松症的发生有关。
【关键词】 血尿酸； 骨密度； 关系
【Abstract】 Objective：To study the correlation between blood uric acid levels and bone mineral density analysis in Liuzhou City.Method：Two thousand one hundred and fifty cases of residents in Liuzhou city for undergoing a medical from December 2010 to December 2014 were retrospectively analyzed，the correlation between residents’ blood uric acid levels and bone mineral density were observed.Result：The bone mineral density in L1-4 parts of residents with normal blood uric acid level were lower than which of patients with high uric acid levels，the difference was statistically significant(P<0.05).In the 1050 cases of male residents，178 patients had the normal bone mass in，whose average level of serum uric acid was (359.12±42.11) μmol/L.539 cases had bone loss，whose average level of serum uric acid was (331.26±54.25) μmol/L；333 cases had bone osteoporosis，whose average level of serum uric acid level was (421.25±32.25) μmol/L；the serum uric acid level of normal bone mass patients was significantly lower than the osteoporosis patients but higher than the patients with bone loss，the differences were statistically significant(F=1161.43，P<0.05).In the 1100 female residents，197 patients had normal bone mass，whose average level of serum uric acid was (298.11±62.32) μmol/L；592 cases had bone loss，whose average level of blood uric acid was (281.12±36.52) μmol/L；311 cases of osteoporosis，whose average level of serum uric acid was (365.21±85.21) μmol/L，the serum uric acid level of normal bone mass patients was significantly lower than the osteoporosis patients，the difference was statistic significant(F=1755.00，P<0.05)；the difference had no statistic significant between the normal bone mass residents and patients with bone loss on the serum uric acid level(P>0.05).Conclusion：The body’s blood uric acid levels are closely associated with the bone mineral density，maintaining the blood uric acid level can prevent the loss of bone mass，but excess uric acid levels will result in the decrease of bone mineral density value，hyperuricemia is associated with the occurrence of osteoporosis., http://www.100md.com(黎荣山 黎文军 王勇 陈慧生 涂强)
【关键词】 血尿酸； 骨密度； 关系
【Abstract】 Objective：To study the correlation between blood uric acid levels and bone mineral density analysis in Liuzhou City.Method：Two thousand one hundred and fifty cases of residents in Liuzhou city for undergoing a medical from December 2010 to December 2014 were retrospectively analyzed，the correlation between residents’ blood uric acid levels and bone mineral density were observed.Result：The bone mineral density in L1-4 parts of residents with normal blood uric acid level were lower than which of patients with high uric acid levels，the difference was statistically significant(P<0.05).In the 1050 cases of male residents，178 patients had the normal bone mass in，whose average level of serum uric acid was (359.12±42.11) μmol/L.539 cases had bone loss，whose average level of serum uric acid was (331.26±54.25) μmol/L；333 cases had bone osteoporosis，whose average level of serum uric acid level was (421.25±32.25) μmol/L；the serum uric acid level of normal bone mass patients was significantly lower than the osteoporosis patients but higher than the patients with bone loss，the differences were statistically significant(F=1161.43，P<0.05).In the 1100 female residents，197 patients had normal bone mass，whose average level of serum uric acid was (298.11±62.32) μmol/L；592 cases had bone loss，whose average level of blood uric acid was (281.12±36.52) μmol/L；311 cases of osteoporosis，whose average level of serum uric acid was (365.21±85.21) μmol/L，the serum uric acid level of normal bone mass patients was significantly lower than the osteoporosis patients，the difference was statistic significant(F=1755.00，P<0.05)；the difference had no statistic significant between the normal bone mass residents and patients with bone loss on the serum uric acid level(P>0.05).Conclusion：The body’s blood uric acid levels are closely associated with the bone mineral density，maintaining the blood uric acid level can prevent the loss of bone mass，but excess uric acid levels will result in the decrease of bone mineral density value，hyperuricemia is associated with the occurrence of osteoporosis., http://www.100md.com(黎荣山 黎文军 王勇 陈慧生 涂强)