ATP依赖的染色质重塑复合物与肺癌研究进展(5)
[16] Fukuoka J，Fujii T，Shih J H，et al.Chromatin remodeling factors and BRM/BRG1 expression as prognostic indicators in non-small cell lung cancer[J].Clin Cancer Res，2004，10(13)：4314-4324.
[17] Hoffman G R，Rahal R，Buxton F，et al.Functional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers[J].Proc Natl Acad Sci USA，2014，111(8)：3128-3133.
[18] Oike T，Ogiwara H，Tominaga Y，et al.A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1[J].Cancer Res，2013，73(17)：5508-5518.
[19] Kozmik Z，Machon O，Kralova J，et al.Characterization of mammalian orthologues of the Drosophila osa gene：cDNA cloning，expression，chromosomal localization，and direct physical interaction with Brahma chromatin-remodeling complex[J].Genomics，2001，73(2)：140-148.
[20] Huang J，Zhao Y L，Li Y，et al.Genomic and functional evidence for an ARID1A tumor suppressor role[J].Genes Chromosomes Cancer，2007，46(8)：745-750.
[21] Zhang Y，Xu X，Zhang M，et al.ARID1A is downregulated in non-small cell lung cancer and regulates cell proliferation and apoptosis[J].Tumour Biol，2014，35(6)：5701-5707.
[22] Manceau G，Letouze E，Guichard C，et al.Recurrent inactivating mutations of ARID2 in non-small cell lung carcinoma[J].Int J Cancer，2013，132(9)：2217-2221.
[23] Papadakis A I，Sun C，Knijnenburg T A，et al.SMARCE1 suppresses EGFR expression and controls responses to MET and ALK inhibitors in lung cancer[J].Cell Res，2015，25(4)：445-458.
[24] Zhang X，Fu L，Xue D，et al.Overexpression of Rsf-1 correlates with poor survival and promotes invasion in non-small cell lung cancer[J].Virchows Arch，2017，470(5)：553-560.
[25] Li Q，Dong Q，Wang E.Rsf-1 is overexpressed in non-small cell lung cancers and regulates cyclinD1 expression and ERK activity[J].Biochem Biophys Res Commun，2012，420(1)：6-10.
[26] Zhao R，Yan Q，Lv J，et al.CHD5，a tumor suppressor that is epigenetically silenced in lung cancer[J].Lung Cancer，2012，76(3)：324-331.
[27] Baykara O，Tansarikaya M，Bulut P，et al.CHD5 is a potential tumor suppressor in non small cell lung cancer(NSCLC)[J].Gene，2017，618：65-68.
[28] Zhang S，Zhou B，Wang L，et al.INO80 is required for oncogenic transcription and tumor growth in non-small cell lung cancer[J].Oncogene，2017，36(10)：1430-1439.
(收稿日期：2017-09-26) (本文編辑：程旭然), http://www.100md.com(黄礼治 荣福)
[17] Hoffman G R，Rahal R，Buxton F，et al.Functional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers[J].Proc Natl Acad Sci USA，2014，111(8)：3128-3133.
[18] Oike T，Ogiwara H，Tominaga Y，et al.A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1[J].Cancer Res，2013，73(17)：5508-5518.
[19] Kozmik Z，Machon O，Kralova J，et al.Characterization of mammalian orthologues of the Drosophila osa gene：cDNA cloning，expression，chromosomal localization，and direct physical interaction with Brahma chromatin-remodeling complex[J].Genomics，2001，73(2)：140-148.
[20] Huang J，Zhao Y L，Li Y，et al.Genomic and functional evidence for an ARID1A tumor suppressor role[J].Genes Chromosomes Cancer，2007，46(8)：745-750.
[21] Zhang Y，Xu X，Zhang M，et al.ARID1A is downregulated in non-small cell lung cancer and regulates cell proliferation and apoptosis[J].Tumour Biol，2014，35(6)：5701-5707.
[22] Manceau G，Letouze E，Guichard C，et al.Recurrent inactivating mutations of ARID2 in non-small cell lung carcinoma[J].Int J Cancer，2013，132(9)：2217-2221.
[23] Papadakis A I，Sun C，Knijnenburg T A，et al.SMARCE1 suppresses EGFR expression and controls responses to MET and ALK inhibitors in lung cancer[J].Cell Res，2015，25(4)：445-458.
[24] Zhang X，Fu L，Xue D，et al.Overexpression of Rsf-1 correlates with poor survival and promotes invasion in non-small cell lung cancer[J].Virchows Arch，2017，470(5)：553-560.
[25] Li Q，Dong Q，Wang E.Rsf-1 is overexpressed in non-small cell lung cancers and regulates cyclinD1 expression and ERK activity[J].Biochem Biophys Res Commun，2012，420(1)：6-10.
[26] Zhao R，Yan Q，Lv J，et al.CHD5，a tumor suppressor that is epigenetically silenced in lung cancer[J].Lung Cancer，2012，76(3)：324-331.
[27] Baykara O，Tansarikaya M，Bulut P，et al.CHD5 is a potential tumor suppressor in non small cell lung cancer(NSCLC)[J].Gene，2017，618：65-68.
[28] Zhang S，Zhou B，Wang L，et al.INO80 is required for oncogenic transcription and tumor growth in non-small cell lung cancer[J].Oncogene，2017，36(10)：1430-1439.
(收稿日期：2017-09-26) (本文編辑：程旭然), http://www.100md.com(黄礼治 荣福)
参见：首页 > 医疗版 > 疾病专题 > 呼吸内科 > 肺肿瘤 > 肺癌