microRNA在急性冠脉综合征中的作用(1)
microRNA在急性冠脉综合征中的作用,miRNA,心血管疾病
【摘要】 microRNA(miRNA)是一类小非编码RNA,在基因表达过程中,通过与靶基因mRNA的3’非编码区结合,从而在转录后调控靶基因表达,miRNA可以调节多达30%的人类基因和控制多种细胞的代谢活动。有研究表明,miRNA在心血管疾病中有重要的调节作用,且miRNA可能成为心血管疾病的重要的生物标记物和药物靶点。急性冠脉综合征(ACS)是心血管疾病中的常见病,本文就miRNA在急性冠脉综合征中的作用做一综述。【关键词】 miRNA; 急性冠脉综合征; 心血管疾病
Role of microRNA in Acute Coronary Syndrome/YUAN Ping,LIANG Yan,TIAN Leigang,et al.//Medical Innovation of China,2018,15(08):144-148
【Abstract】 microRNA(miRNA) is a class of small non-coding mRNAs that exert their posttranscriptional regulatory effects by targeting 3’ untranslated region(3’UTR) of corresponding miRNA.It has been estimated that miRNA may regulate up to 30% of human genes and control various cellular processes.Previous studies have suggested that miRNA may play an important role during cardiovascular disease progression.Acute coronary syndrome(ACS) is a common disease in cardiovascular disease ......
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