肺癌临床诊断中应用PET/CT检查的价值与结果回顾分析(1)
【摘要】 目的：分析肺癌臨床诊断中应用PET/CT检查的价值与结果。方法：回顾性分析2016年6月-2017年12月本院收治的可疑肺部恶性病变患者88例的临床资料。患者均实施组织病理学检查和PET/CT检查，以病理学检查为金标准，比较肺部良性病变与肺癌的18F-FDG摄取差异，并总结分析PET/CT检查误诊原因。结果：经组织病理学检查，本组88例患者中确诊为肺部良性病变者20例(22.73%)、肺癌者68例(77.27%)，经PET/CT检查确诊为肺部良性病变者13例(14.77%)、肺癌者67例(76.14%)，其中1例阳性假瘤(炎性假瘤)，3例结核、3例机化性肺炎被误诊为肺癌，1例中央型肺癌误诊为肺炎肺不张。PET/CT检查肺癌的特异度为65.0%(13/20)、敏感度为98.5%(67/68)。经PET/CT检查，肺良性病变组织SUVmax(7.25±3.03)低于肺癌组织的(10.68±5.47)，比较差异有统计学意义(P<0.05)。结论：在临床诊断肺癌的过程中，采用PET/CT检查是一种综合诊断方式，且与肺良性病变组织相比，肺癌组织经PET/CT检查的18F-FDG摄取值较高，而造成诊断结果假阳性较高的原因主要为少数机化性肺炎和结核的PET/CT表现与肺癌类似。
, 百拇医药
【关键词】 肺癌； PET/CT检查； 临床诊断； 应用价值； 回顾分析
【Abstract】 Objective：To analyze the value and results of the application of PET/CT in the clinical diagnosis of lung cancer.Method：The clinical data of 88 patients with suspicious pulmonary malignancy who admitted to our hospital from June 2016 to December 2017 were retrospectively analyzed.All patients underwent histopathological examination and PET/CT.The pathological examination was the gold standard，the difference of 18F-FDG uptake between lung benign lesions and lung cancer was compared，and the misdiagnosis causes of PET/CT examinations were analyzed.Result：According to histopathological examination，there were 20 cases(22.73%) diagnosed as benign lung lesions and 68 cases(77.27%) diagnosed with lung cancer in 88 cases.According to PET/CT examination，13 cases(14.77%) diagnosed as benign lung lesions and 67 cases(76.14%) diagnosed with lung cancer，among them，1 case of positive pseudotumor，3 cases of tuberculosis and 3 cases of systemic pneumonia were misdiagnosed as lung cancer，and 1 case of central lung cancer was misdiagnosed as pneumoconiosis.The specificity of PET/CT for lung cancer was 65.0%(13/20) and sensitivity was 98.5%(67/68).After PET/CT examination，the SUVmax in lung benign lesions was(7.25±3.03)，which was significantly lower than (10.68±5.47) in lung cancer tissues，the difference was statistically significant(P<0.05).Conclusion：PET/CT is a comprehensive diagnostic method in the clinical diagnosis of lung cancer，compared with benign lung tissue，lung cancer tissue underwent PET/CT examination with significantly higher 18F-FDG uptake，and the reason for the higher false positives was mainly due to the similar PET/CT performance of a few institutionalized pneumonias and tuberculosis.
【Key words】 Lung cancer； PET/CT examination； Clinical diagnosis； Application value； Retrospective analysis
First-author’s address：Jinzhou Central Hospital，Jinzhou 121000，China, 百拇医药(杜宁)
, 百拇医药
【关键词】 肺癌； PET/CT检查； 临床诊断； 应用价值； 回顾分析
【Abstract】 Objective：To analyze the value and results of the application of PET/CT in the clinical diagnosis of lung cancer.Method：The clinical data of 88 patients with suspicious pulmonary malignancy who admitted to our hospital from June 2016 to December 2017 were retrospectively analyzed.All patients underwent histopathological examination and PET/CT.The pathological examination was the gold standard，the difference of 18F-FDG uptake between lung benign lesions and lung cancer was compared，and the misdiagnosis causes of PET/CT examinations were analyzed.Result：According to histopathological examination，there were 20 cases(22.73%) diagnosed as benign lung lesions and 68 cases(77.27%) diagnosed with lung cancer in 88 cases.According to PET/CT examination，13 cases(14.77%) diagnosed as benign lung lesions and 67 cases(76.14%) diagnosed with lung cancer，among them，1 case of positive pseudotumor，3 cases of tuberculosis and 3 cases of systemic pneumonia were misdiagnosed as lung cancer，and 1 case of central lung cancer was misdiagnosed as pneumoconiosis.The specificity of PET/CT for lung cancer was 65.0%(13/20) and sensitivity was 98.5%(67/68).After PET/CT examination，the SUVmax in lung benign lesions was(7.25±3.03)，which was significantly lower than (10.68±5.47) in lung cancer tissues，the difference was statistically significant(P<0.05).Conclusion：PET/CT is a comprehensive diagnostic method in the clinical diagnosis of lung cancer，compared with benign lung tissue，lung cancer tissue underwent PET/CT examination with significantly higher 18F-FDG uptake，and the reason for the higher false positives was mainly due to the similar PET/CT performance of a few institutionalized pneumonias and tuberculosis.
【Key words】 Lung cancer； PET/CT examination； Clinical diagnosis； Application value； Retrospective analysis
First-author’s address：Jinzhou Central Hospital，Jinzhou 121000，China, 百拇医药(杜宁)
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