黄睿婷 张鹏横 阮璐薇 任秋萍

    【摘要】 情志变化是围绝经期肝郁证的主要临床表现，亦是肝郁病理的外在表现，与“肝主疏泄，调节情志”密切相关。中医肝调节情志的调控因素复杂，其中以大脑的中枢调控为主，而神經环路又是中枢调控的基本单位。因此，本文以肝脑相维为切入点，从肝调节情志所涉及的神经环路角度，揭示围绝经期肝郁证的病理机制，旨在丰富“肝主疏泄，调节情志”的科学内涵，以期为相关研究提供新的方法与策略。

    【关键词】 肝脑相关 情志 神经环路 围绝经期 肝郁证

    [Abstract] Emotional change is the main clinical manifestation of liver stagnation in perimenopausal period， and also the external manifestation of liver depression pathology， which correlates with “liver controlling dispersion and regulating emotion”. Its complex that the factors of liver regulating emotion， among which the central regulation of brain is the main one， whats more neuronal circuit is the basic unit of central regulation. Therefore， in this paper， from the perspective of neuronal circuit involved in liver regulating emotion， the liver-brain correlation is used as the entry point， to reveal the pathological mechanism of liver stagnation in perimenopausal period. In order to enrich the scientific connotation of “liver controlling dispersion and regulating emotion”， as well as provide new methods and strategies for research. ......