刘瑞真 吴小末

    【关键词】 IL-17a HaCaT细胞 IL-6 IL-22 IL-23 STAT3

    [Abstract] Objective： To explore the effect of interleukin-17a (IL-17a) on the expression of IL-6， IL-22， IL-23 in human immortalized keratinocytes (HaCaT) cells and possible mechamism of IL-17a regulating IL-6， IL-22， IL-23 in keratinocytes. Method： HaCaT cells were divided into blank control group (DMEM high-glucose medium only)， induction group (DMEM high-glucose medium containing 80 μg/L IL-17a) and inhibitor group (DMEM high-glucose medium containing 80 μg/L IL-17a and 10 μg/L STAT3 inhibitor Piceatannol). After 48 h ......