结核性脑膜炎患者预后情况调查及其相关影响因素分析
刘子林 肖绍武 叶琳 况卫丰 张丽婷 周丽 张齐龙【摘要】 目的:探讨结核性脑膜炎(tuberculous meningitis,TBM)患者预后情况及其相关影响因素。方法:回顾性分析2019年1月-2021年7月就诊于本院的60例TBM患者的临床资料,分析TBM患者预后情况及其相关影响因素。结果:60例TBM患者中,預后良好39例(65.00%),预后不良21例(35.00%)。单因素分析显示,脑积水、意识障碍、脑脊液蛋白含量、脑脊液氯化物含量与TBM患者预后有关,差异均有统计学意义(P<0.05)。年龄、治疗前病程、性别、肢体瘫痪、癫痫发作、疾病分期、激素治疗、合并颅外结核、脑压、脑脊液葡萄糖含量和白细胞计数与TBM患者预后无关,差异均无统计学意义(P>0.05)。多因素分析显示,脑积水、意识障碍、脑脊液蛋白含量≥4 000 g/L、脑脊液氯化物含量<115 mmol/L是影响TBM患者预后的危险因素(P<0.05)。结论:TBM患者预后较差,其受脑积水、意识障碍、脑脊液蛋白含量、脑脊液氯化物含量影响。
【关键词】 结核性脑膜炎 脑积水 预后 意识障碍
Investigation of Prognosis of Tuberculous Meningitis Patients and Analysis of Related Influencing Factors/LIU Zilin, XIAO Shaowu, YE Lin, KUANG Weifeng, ZHANG Liting, ZHOU Li, ZHANG Qilong. //Medical Innovation of China, 2021, 18(35): 0-072
[Abstract] Objective: To investigate the prognosis and related factors of tuberculous meningitis (TBM). Method: The clinical data of 60 TBM patients admitted to our hospital from January 2019 to July 2021 were retrospectively analyzed, and the prognosis and related factors of TBM patients were analyzed. Result: Among the 60 patients with TBM ......
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