高强 唐晶

    【摘要】 目的：鉴定肛周脓肿患者的病原菌分布情况，分析其对常用抗菌药物的耐药性。方法：选取2018年1月-2020年12月吉安市中心人民醫院收治125名肛周脓肿患者，对其送检的肛周脓液进行培养，采用珠海美华MA-120半自动细菌鉴定仪进行细菌鉴定与药敏试验。结果：125例患者的脓液标本中共分离培养出135株菌，其中革兰阴性菌108例，占比80%;革兰阳性菌27株，占比20%;排名前三的细菌分别为大肠埃希菌99株(73.3%)、肺炎克雷伯菌8株(5.9%)和金黄色葡萄球菌7株(5.2%)。大肠埃希菌产ESBL菌株为42.42%(42/99)，高于肺炎克雷伯菌12.50%(1/8)。耐甲氧西林金黄色葡萄球菌(MRSA)占比28.6%(2/7)，星座链球菌对红霉素和克林霉素的敏感率均为33.3%，对其他常用抗生素的敏感率均为100%。结论：肛周脓肿患者的病原菌分布存在一定差异，病原菌以大肠埃希菌为主。临床用药期间，需要根据细菌培养结果与耐药性分析结果，调整用药方案，避免选药不合理影响药物的治疗效果。

    【关键词】 肛周脓肿 细菌鉴定 病原菌分布 细菌耐药

    Pathogen Distribution in Perianal Abscess and Their Resistance to Antibiotics/GAO Qiang， TANG Jing. //Medical Innovation of China， 2022， 19(13)： -165

    [Abstract] Objective： To determine the pathogen distribution in patients with perianal abscess and analyze their resistance to common antibiotics. Method： A total of 125 patients with perianal abscess admitted to Ji’an Central People’s Hospital from January 2018 to December 2020 were selected and their perianal abscess samples were cultured. Bacterial identification and drug sensitivity test were performed using Zhuhai Meihua MA-120 semi-automatic bacterial identification instrument. Result： A total of 135 strains were isolated and cultured from the pus samples of 125 patients ......