克日曼·帕尔哈提 穆热迪力·木合塔尔 阿布来提·阿不都哈尔

    【摘要】 应激性溃疡预防在重症患者中的应用十分普遍，但随着现代医疗水平的提高，与应激相关的消化道出血的发生率下降，且越来越多的研究开始关注预防药物的副作用和过度使用的现状，使得应激性溃疡预防药物的常规使用受到质疑。本文通过综述应激性溃疡的发病机制、危险因素和不同预防策略的优势及其弊端，旨在为应激性溃疡预防在重症患儿中的合理应用提供依据。

    【关键词】 应激性溃疡 预防 重症监护

    Research Advance of Stress Ulcer Prophylaxis in Critically Ill Children/PAERHATI Keriman， MUHETAER Muredili， ABUDUHAER Abulaiti. //Medical Innovation of China， 2023， 20(10)： -188

    [Abstract] Stress ulcer prophylaxis is widely used in critically ill patients， but with modern medical advances， the incidence of stress-related gastrointestinal bleeding has declined and a growing number of studies are focusing on the side effects and overuse of prophylactic drugs， which has brought into question the routine use of prophylactic drugs. This article reviews the pathogenesis， risk factors and benefits and drawbacks of different prevention strategies of stress ulcer， aiming to provide a basis for the rational application of stress ulcer prophylaxis in critically ill children. ......