【摘要】 耳鸣是一种常见临床症状，慢性耳鸣患者的发生发展与焦虑、抑郁等情绪障碍有关，长期耳鸣困扰会造成患者精神甚至行为上的异常。严重失代偿耳鸣患者中，40%～60%患有重度抑郁症，15%～60%患有焦虑症。边缘系统作为控制行为和情绪表达的重要结构，在耳鸣合并焦虑、抑郁中起重要的调节作用。因此，本文就耳鸣与焦虑、抑郁的发生情况、边缘系统参与相关机制研究进展及目前的治疗方案做一综述，为临床医生提供诊疗思路，改善患者耳鸣患者的健康状况。

    【关键词】 耳鸣 焦虑 抑郁 边缘系统

    Research Status of Chronic Tinnitus Patients Complicated with Anxiety and Depression/LI Lan， YAO Jun， LIU Leifeng， XU Mei. //Medical Innovation of China， 2023， 20(22)： -185

    [Abstract] Tinnitus is a common clinical symptom. The occurrence and development of chronic tinnitus patients are related to anxiety， depression and other emotional disorders. Long-term tinnitus disturbance will cause mental and even behavioral abnormalities in patients. In patients with severe decompensated tinnitus， 40%～60% suffer from severe depression， and 15%～60% suffer from anxiety. As an important structure controlling behavior and emotional expression， the limbic system plays an important regulatory role in tinnitus combined with anxiety and depression. Therefore， this paper reviews the development of tinnitus， anxiety and depression， and the related mechanism of limbic system participation ......