【摘要】 轻型创伤性脑损伤(mTBI)，通常称为脑震荡，是最常见的神经系统疾病之一，其大脑功能紊乱的机制仍不清楚。目前对mTBI的诊断在很大程度上依赖于患者主观的临床症状，而这些症状往往不可靠和/或非特异性。功能性磁共振成像(fMRI)应用于mTBI的评估，弥补了传统结构影像学检查在mTBI影像学诊断中的局限性，可提供客观影像学依据，使理解mTBI发病机制中神经网络及脑区之间的相互作用成为可能。任务态fMRI和静息态fMRI从不同角度深入了解mTBI后神经病理学改变，可更准确地定位受损脑功能区，从而全面评估颅脑损伤的严重程度，大大提高mTBI的早期诊断准确性，并在预后评估中发挥重要作用。

    【关键词】 功能性磁共振成像 脑震荡 轻型创伤性脑损伤

    Application Progress of Functional Magnetic Resonance Imaging in the Diagnosis of Mild Traumatic Brain Injury/GAN Xi， CAO Guanbai， LIU Chuling. //Medical Innovation of China， 2023， 20(26)： -188

    [Abstract] Mild traumatic brain injury (mTBI)， commonly known as concussion， is one of the most common neurological disorders， and the mechanisms of brain dysfunction remain unclear. At present， the diagnosis of mTBI depends largely on patients' subjective clinical symptoms， which are often unreliable and/or non-specific. The application of functional magnetic resonance imaging (fMRI) in the evaluation of mTBI makes up for the limitations of traditional structural imaging in the imaging diagnosis of mTBI， provides an objective imaging basis， and makes it possible to understand the interaction between neural network and brain regions in the pathogenesis of mTBI. Task-based fMRI and resting-state fMRI can deeply understand the neuropathological changes after mTBI from different angles ......