宋静静 樊琳琳

    【摘要】 维生素D缺乏普遍存在于人群中，维生素D的经典作用与骨骼、肾脏和肠道有关。近年来研究发现，维生素D还与免疫、生殖、内分泌、肌肉及大脑、皮肤和肝脏相关。维生素D与自身免疫性甲状腺疾病(autoimmune thyroid disease，AITD)之间的关系也被广泛研究，但只有少数在人类中进行的随机临床试验研究了维生素D在预防或治疗免疫性疾病中的可能作用。本文的目的是回顾最近维生素D与AITD之间的文献，分析其可能存在的机制，以及补充维生素D在AITD中的潜在意义。

    【关键词】 维生素D 自身免疫性甲状腺疾病 桥本甲状腺炎 格雷夫斯病 格雷夫斯眼病

    Research Progress of Vitamin D and Autoimmune Thyroid Disease/SONG Jingjing， FAN Linlin. //Medical Innovation of China， 2023， 20(35)： -188

    [Abstract] Vitamin D deficiency is common in humans， and the classic effects of vitamin D are related to the bones， kidneys and intestines. In recent years， studies had found that vitamin D is also associated with immunity， reproduction， endocrine， muscle， brain， skin and liver. The relationship between vitamin D and autoimmune thyroid disease (AITD) has also been extensively studied， but only a handful of randomized clinical trials in humans have investigated the possible role of vitamin D in the prevention or treatment of immune diseases. The aim of this article was to review the recent literature on vitamin D and AITD ......