王海华 许鸿东

    【摘要】 目的：探討右美托咪定联合无创正压通气在慢阻肺中的应用及对血流动力学的影响。方法：选择2021年1月—2022年1月在漳州正兴医院接受治疗的73例慢阻肺患者，采用随机数表法分为试验组(n=37)和对照组(n=36)。对照组给予无创正压通气治疗，试验组在对照组基础上加用右美托咪定治疗。比较两组临床疗效、心率、平均动脉压、动脉血二氧化碳分压(PaCO2)、动脉血氧分压(PaO2)、pH值及不良反应发生情况。结果：试验组总有效率为91.89%，对照组为72.22%，两组比较，差异有统计学意义(P0.05)。结论：慢阻肺患者应用右美托咪定联合无创正压通气治疗有较好的效果，可有效改善血流动力学，安全性高。

    【关键词】 右美托咪定 无创正压通气 慢阻肺 血流动力学

    Application of Dexmedetomidine Combined with Non-invasive Positive Pressure Ventilation in COPD and Its Influence on Hemodynamics/WANG Haihua， XU Hongdong. //Medical Innovation of China， 2024， 21(02)： 0-065

    [Abstract] Objective： To investigate the application of Dexmedetomidine combined with non-invasive positive pressure ventilation in chronic obstructive pulmonary diseases and its influence on hemodynamics. Method： A total of 73 patients with chronic obstructive pulmonary diseases treated in Zhangzhou Zhengxing Hospital from January 2021 to January 2022 were selected and divided into experimental group (n=37) and control group (n=36) according to random number table method. The control group was treated with non-invasive positive pressure ventilation ......