熊菲 朱坤

    【摘要】 目的：探究窄谱中波紫外线(NB-UVB)联合左西替利嗪对特应性皮炎患儿嗜酸性粒细胞(EOS)、免疫球蛋白E(IgE)水平的影响。方法：选取九江学院附属医院2020年1月—2023年6月收治的特应性皮炎患儿102例，根据随机数字表法分为试验组(51例)，常规组(51例)。常规组进行NB-UVB治疗，试验组采用NB-UVB联合左西替利嗪治疗。治疗结束后评估患儿临床效果，比较治疗前后特应性皮炎评分(SCORAD)及EOS、血清总IgE变化情况，统计比较治疗期间的不良反应发生情况。结果：试验组、常规组治疗总有效率分别为94.12%、78.43%，试验组较常规组高，差异有统计学意义(P0.05)；治疗后，两组血清EOS、IgE水平均较治疗前降低，试验组均较常规组低(P0.05)。结论：NB-UVB联合左西替利嗪能够提高特应性皮炎患儿的临床效果，促进患儿恢复，降低血清EOS、IgE水平，安全性较高。

    【关键词】 左西替利嗪 不良反应 特应性皮炎 皮肤发红 嗜酸性粒细胞

    Effects of NB-UVB Combined with Levocetirizine on EOS and IgE Levels in Children with Atopic Dermatitis/XIONG Fei， ZHU Kun. //Medical Innovation of China， 2024， 21(15)： 0-037

    [Abstract] Objective： To investigate the effects of narrow bound ultra violet B light (NB-UVB) combined with Levocetirizine on eosinophile (EOS) and immunoglobulin E (IgE) levels in children with atopic dermatitis. Method： A total of 102 children with atopic dermatitis admitted to Jiujiang University Affiliated Hospital from January 2020 to June 2023 were selected and divided into experimental group (51 cases) and conventional group (51 cases) according to random number table method. The conventional group was treated with NB-UVB ......