【摘要】 目的：探讨内镜下乳头括约肌小切开术联合球囊扩张治疗10 mm以上胆总管结石的效果及安全性。方法：回顾性分析2021年6月—2023年6月宜春市第二人民医院收治的132例10 mm以上胆总管结石患者的临床资料，根据术中是否应用球囊扩张分为球囊组(n=86)和非球囊组(n=46)。比较两组临床指标、并发症发生率及手术前后的生化指标。结果：球囊组总取石成功率、一次性取石成功率均高于非球囊组，取石时间短于非球囊组，差异均有统计学意义(P<0.05)。两组并发症发生率比较，差异无统计学意义(P>0.05)。术后，球囊组谷丙转氨酶(ALT)、总胆红素、血清淀粉酶均低于非球囊组，差异均有统计学意义(P<0.05)。结论：内镜下乳头括约肌小切开术联合球囊扩张治疗10 mm以上胆总管结石取石成功率较高，且操作时间短，能够改善患者生化指标水平，具有较高的安全性。

    【关键词】 内镜下乳头括约肌小切开术 球囊扩张 胆总管结石 安全性

    Effectiveness and Safety of Endoscopic Papillary Sphincter Sphincterotomy Combined with Balloon Dilatation in the Treatment of Choledocholith over 10 mm/YUAN Yan， CHEN Qiong， XI Yu. //Medical Innovation of China， 2024， 21(27)： 0-031

    [Abstract] Objective： To investigate the efficacy and safety of endoscopic papillary sphincter sphincterotomy combined with balloon dilation in the treatment of choledocholith over 10 mm. Method： The clinical data of 132 patients with choledocholith over 10 mm admitted to Yichun Second People's Hospital from June 2021 to June 2023 were retrospectively analyzed. The patients were divided into balloon group (n=86) and non-balloon group (n=46) according to whether balloon dilation was used during the operation. The clinical index ......