【摘要】 止血带是骨科手术常用的止血设备，应用于四肢手术，可以维持清晰、无血的手术视野，减少失血量，加速康复。同时，止血带的使用会给患者带来许多不良反应，包括炎症反应、缺血再灌注损伤(ischemia reperfusion injury，IRI)等，严重甚至危及生命。本文对止血带诱发IRI的机制、影响及预防治疗措施做了总结与探讨，旨在为预防治疗止血带诱发IRI提供新的理论依据。

    【关键词】 止血带 缺血再灌注损伤 缺血预处理

    Research Progress on Prevention and Treatment of Tourniquet Induced Ischemia Reperfusion Injury/YAO Huijie， ZHAO Tao， LI Ximing. //Medical Innovation of China， 2024， 21(29)： -188

    [Abstract] Tourniquet is a hemostatic device commonly used in orthopedic surgery. It can maintain a clear and bloodless surgical field of view， reduce blood loss and accelerate recovery. At the same time， the use of tourniquet would cause a lot of adverse reactions to patients， including inflammation and ischemia reperfusion injury (IRI)， which is serious or even life-threatening. This paper summarizes and discusses the mechanism， influence and preventive treatment measures of tourniquet induced IRI， aiming to provide a new theoretical basis for the prevention and treatment of tourniquet induced IRI.

    [Key words] Tourniquet Ischemia reperfusion injury Ischemic preconditioning ......