血小板免疫功能与自身免疫性疾病的关系
【摘要】 血小板传统上被认为主要参与止血过程。然而,近年来的研究表明,血小板在免疫调节中也扮演着关键角色。血小板表面具有多种免疫相关受体和分子,使其能够与免疫细胞相互作用,参与机体免疫应答。同时,血小板释放的细胞因子和化学介质也参与了炎症反应和免疫反应的调节过程。本文就血小板在自身免疫性疾病中的作用进行综述。【关键词】 血小板免疫功能 自身免疫性疾病 血小板胞外囊泡 血小板参数
Relationship between Platelet Immune Function and Autoimmune Diseases/WANG Xuzhong, LUO Pengli. //Medical Innovation of China, 2024, 21(30): -177
[Abstract] Traditionally, platelets have been thought to primarily participate in the hemostatic process. However, recent studies have shown that platelets also play a key role in immune regulation. The surface of platelets has a variety of immune-related receptors and molecules, which enable them to interact with immune cells and participate in the body's immune response. At the same time, cytokines and chemical mediators released by platelets are also participated in the regulation of inflammation and immune response. This article reviews the role of platelets in autoimmune diseases.
[Key words] Platelet immune function Autoimmune diseases Platelet extracellular vesicles Platelet parameters
First-author's address: Department of Nephrology ......
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