【摘要】 目的：探究腹腔镜胆总管探查术(LCBDE)+腹腔镜胆囊切除术(LC)一步法治疗胆囊结石合并胆总管结石(CCWC)的临床效果。方法：选取温州医科大学附属衢州医院2021年1月—2024年

    1月收治的80例CCWC患者，按随机数字表法分为两组，各40例。对照组行内镜逆行胰胆管造影(ERCP)+LC序贯二步法治疗，观察组行LCBDE+LC一步法治疗。比较两组手术情况、术后恢复情况、血清炎症因子水平、应激反应、肝胆功能、并发症发生情况。结果：观察组总手术时间、住院时间、术后排气时间及肠鸣音恢复时间均短于对照组，差异均有统计学意义(Plt;0.05)；观察组术后血清炎症因子水平、应激反应指标水平及肝胆功能指标水平均较对照组低，并发症发生率低于对照组，差异均有统计学意义(Plt;0.05)。结论：LCBDE+LC一步法治疗CCWC效果更佳，利于减轻手术应激反应，减少炎症因子释放，且手术效率更高，术后恢复时间短，并发症少。

    【关键词】 胆囊结石 胆总管结石 腹腔镜胆总管探查术 腹腔镜胆囊切除术 炎症因子

    Effect of LCBDE+LC One-step Method on Postoperative Recovery and Serum Inflammatory Factors Levels in Patients with Cholecystolithiasis Combined with Choledocholithiasis/WANG Jin， JIANG Ming， YE Weikang， SU Qizhi. //Medical Innovation of China， 2024， 21(31)： 0-053

    [Abstract] Objective： To explore the clinical effect of laparoscopic common bile duct exploration (LCBDE) and laparoscopic cholecystectomy (LC) in the treatment of cholecystolithiasis combined with choledocholithiasis stones (CCWC). Method： A total of 80 patients with CCWC admitted to Quzhou Affiliated Hospital of Wenzhou Medical University from January 2021 to January 2024 were selected and divided into two groups according to random number table method ......