【摘要】 恶性肿瘤是全球范围内导致死亡的主要原因之一，其发病率和死亡率呈现逐年上升的趋势。尽管恶性肿瘤检查手段取得了一定的进展，但恶性肿瘤的早期诊断和疗效评估仍然是一个巨大的挑战。近年来，异常糖链糖蛋白(tumor abnormal protein，TAP)作为肿瘤标志物在多种恶性肿瘤诊治中的作用逐渐受到关注。本文旨在综述TAP在常见恶性肿瘤诊断、治疗及预后评估中的应用，总结TAP在恶性肿瘤诊治中的研究现状及未来发展方向。

    【关键词】 恶性肿瘤 异常糖链糖蛋白 早期诊断 预后评估

    Research Progress of Tumor Abnormal Protein in the Diagnosis and Treatment of Malignant Tumors/ZHAO Dong， CAI Fei， LIU Xuefei， FAN Guangye， ZHENG Zhendong. //Medical Innovation of China， 2025， 22(02)： -170

    [Abstract] Malignant tumors is one of the main causes of death worldwide， and its morbidity and mortality are increasing year by year. Although some progress has been made in the examination of malignant tumors， the early diagnosis and curative effect evaluation of malignant tumors is still a huge challenge. In recent years， the role of tumor abnormal protein (TAP) as a tumor marker in the diagnosis and treatment of various malignant tumors has attracted increasing attention. This article aims to review the application of TAP in the diagnosis， treatment and prognosis assessment of common malignant tumors， and summarize the research status and future development direction of TAP in the diagnosis and treatment of malignant tumors. ......