【摘要】 目的：分析桂枝茯苓胶囊联合地诺孕素对卵巢子宫内膜异位囊肿(OEC)术后患者卵巢功能与血清肿瘤标志物的影响。方法：选取2022年6月—2023年9月乐平市中医医院妇产科收治的90例OEC术后患者作为研究对象，根据治疗方案分为地诺孕素组(n=42)和联合组(n=48)。地诺孕素组给予地诺孕素治疗，联合组在地诺孕素组的基础上给予桂枝茯苓胶囊治疗。对比两组临床疗效、中医症候积分、卵巢功能[卵泡刺激素(FSH)、黄体生成素(LH)、雌二醇(E2)]、血清肿瘤标志物[糖类抗原125(CA125)、糖类抗原199(CA19-9)]。结果：联合组总有效率显著高于地诺孕素组，差异有统计学意义(Plt;0.05)。治疗后，两组腰膝酸软、经行腹痛、神疲乏力评分及E2、CA125、CA19-9均低于治疗前，FSH、LH均高于治疗前，且联合组腰膝酸软、经行腹痛、神疲乏力评分及E2、CA125、CA19-9均低于地诺孕素组，FSH、LH均高于地诺孕素组，差异均有统计学意义(Plt;0.05)。结论：桂枝茯苓胶囊联合地诺孕素治疗OEC术后患者具有良好的临床疗效，可促进卵巢功能的恢复，降低血清CA125、CA19-9水平。

    【关键词】 桂枝茯苓胶囊 地诺孕素 卵巢子宫内膜异位囊肿 卵巢功能 血清肿瘤标志物

    Effects of Guizhi Fuling Capsules Combined with Dienogest on Ovarian Function and Serum CA125 and CA19-9 of in Patients with OEC after Operation/TONG Yinzhi. //Medical Innovation of China， 2025， 22(04)： 0-060

    [Abstract] Objective： To analyze the effects of Guizhi Fuling Capsules combined with Dienogest on ovarian function and serum tumor markers in patients with ovarian endometrial cyst (OEC) after operation. Method： A total of 90 patients with OEC after operation treated in the Obstetrics and Gynecology Department of Leping Hospital of Traditional Chinese Medicine from June 2022 to September 2023 were selected as the study objects ......