【摘要】 目的：探究宫腔镜电切术联合地屈孕酮对子宫内膜息肉患者炎症因子及复发情况的影响。方法：选取瑞金市妇幼保健院2022年3月—2023年3月收治的88例子宫内膜息肉患者作为研究对象，进行回顾性分析。根据治疗方式不同将患者分为两组：单一组(n=42，采取宫腔镜电切术治疗)、联合组(n=46，采取宫腔镜电切术联合地屈孕酮治疗)。对比两组月经情况、子宫内膜厚度、炎症因子水平及复发情况。结果：术前两组月经情况及子宫内膜厚度比较，差异均无统计学意义(Pgt;0.05)；术后6个月，两组月经期均缩短，月经量均减少，子宫内膜厚度均减小，且联合组较单一组月经期短[(5.21±1.65)d vs(7.13±1.76)d]、月经量少[(64.47±8.75)mL vs(71.47±9.31)mL]、子宫内膜厚度小[(4.69±1.12)mm vs(6.12±1.88)mm]，差异均有统计学意义(Plt;0.05)。术前两组炎症因子水平比较，差异均无统计学意义

    (Pgt;0.05)；术后1个月两组炎症因子水平均降低，且与单一组比较，联合组白细胞介素-6 [(8.06±2.45)ng/L

    vs(9.65±3.01)ng/L]、C反应蛋白[(6.35±1.59)mg/L vs(7.31±1.66)mg/L]、肿瘤坏死因子-α

    [(3.04±0.98)ng/L vs(4.35±1.24)ng/L]水平均低，差异均有统计学意义(Plt;0.05)。联合组复发率低于单一组(4.35% vs 19.05%)，差异有统计学意义(Plt;0.05)。结论：宫腔镜电切术联合地屈孕酮治疗子宫内膜息肉，可改善患者月经和子宫内膜情况，减轻炎症反应，降低复发率低。

    【关键词】 宫腔镜电切术 地屈孕酮 子宫内膜息肉 炎症因子 复发

    Effects of Hysteroscopic Electrocision Combined with Dydrogesterone on Inflammatory Factors and Recurrence in Patients with Endometrial Polyps/YANG Xingling， WANG Qun， WEI Li. //Medical Innovation of China， 2025， 22(04)： 0-063

    [Abstract] Objective： To investigate the effects of hysteroscopic electrocision combined with Dydrogesterone on inflammatory factors and recurrence in patients with endometrial polyps. Method： A total of 88 patients with endometrial polyps admitted to Ruijin Maternal and Child Health Hospital from March 2022 to March 2023 were selected as the research subjects for retrospective analysis. Patients were divided into two groups according to different treatment methods： single group (n=42 ......