【摘要】 特发性肺纤维化(idiopathic pulmonary fibrosis，IPF)是一种进行性发展且病死率极高的间质性肺疾病。目前临床缺乏有效防治IPF的措施，故危险因素的识别在疾病防治过程中显得极其重要。如何防控影响IPF发生与预后的危险因素，是有效预防IPF发生和抑制IPF持续进展的关键。本文国内外最新研究关于IPF的危险因素的进展做一阐述，以期提高临床医生对IPF的认识，从而及时规避风险，及时选择最佳防治措施。

    【关键词】 特发性肺纤维化 危险因素 年龄 胃食管反流病

    Research Progress on Risk Factors of Idiopathic Pulmonary Fibrosis/WU Nan， WU Zhengyuan， YU Liyue， HAO Junhua， ZHANG Ming， LIU Zhi. //Medical Innovation of China， 2025， 22(04)： -168

    [Abstract] Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease with a high fatality rate. At present， there is a lack of effective prevention and treatment measures of IPF， so the identification of risk factors is extremely important in the process of disease prevention and treatment. How to prevent and control the risk factors affecting the occurrence and prognosis of IPF is the key to effectively prevent the occurrence of IPF and inhibit the continuous progress of IPF. In this paper， the latest research on the risk factors of IPF at home and abroad is described， in order to improve the clinician's understanding of IPF ......