【摘要】 随着乙型肝炎疫苗的广泛使用和抗病毒药物的研发，病毒性肝炎的发病率大幅下降，而代谢性肝病的发病率却逐年上升。代谢性肝病可导致肝纤维化、肝硬化甚至肝癌，严重威胁人类健康。目前肝硬化是该疾病最大的威胁，关于该疾病在肝硬化阶段的研究较为缺乏，因此研究该病肝硬化阶段的诊断及治疗，对该病的分级和管理、改善预后、降低发病率与死亡率都至关重要，本文综述了代谢相关脂肪性肝病(metabolic associated fatty liver disease，MAFLD)相关性肝硬化的更名、诊断及治疗，为今后临床研究及用药提供参考。

    【关键词】 代谢相关脂肪性肝病 肝硬化 诊断 治疗

    Research Progress of Cirrhosis Associated with Metabolic Associated Fatty Liver Disease/WANG Huahua， SUN Lihua. //Medical Innovation of China， 2025， 22(04)： -178

    [Abstract] With the wide use of hepatitis B vaccine and the development of antiviral drugs， the incidence of viral hepatitis has decreased significantly， while the incidence of metabolic liver disease has increased year by year. Metabolic liver disease can lead to liver fibrosis， cirrhosis and even liver cancer， which is a serious threat to human health. At present， cirrhosis is the biggest threat of this disease， and there are few studies on this disease in the cirrhosis stage. Therefore， studying the diagnosis and treatment of this disease in the cirrhosis stage is crucial for the classification and management of this disease ......