【摘要】 针对小胶质细胞参与癫痫发病机制的研究进展，本文通过概述小胶质细胞的功能、分型以及在癫痫中的作用，深入探讨了小胶质细胞在癫痫发生和发展中的重要性。有关小胶质细胞激活、细胞因子释放、信号通路传导等方面的探讨都对进一步了解癫痫的发病机制提供了有益的信息。同时，识别小胶质细胞在癫痫中的作用有助于为治疗癫痫寻找新的治疗靶点。因此，本文对于揭示癫痫的病理生理机制以及开发相关治疗手段具有重要的研究意义。

    【关键词】 小胶质细胞 癫痫 细胞因子 信号通路

    Research Progress on the Involvement of Microglia in the Pathogenesis of Epilepsy

    [Abstract] In light of the research progress on the involvement of microglial cells in the pathogenesis of epilepsy， this article provides an overview of the functions， classifications， and roles of microglial cells in epilepsy， delving into the significant of microglial cells in the onsets and progression of epilepsy. Discussions on microglial cell activation， cytokine release， and signal transduction pathways provide valuable insights for a deeper understanding of the mechanisms underlying epilepsy. Furthermore， indentifying the role of microglial cells in epilepsy can help identify new therapeutic targets for epilepsy treatment. Therefore， this article holds significance research implications for revealing the pathophysiological mechanism of epilepsy and developing related treatments. ......