Effect of Danhong Injection Combined with Dexmedetomidine on Postoperative Defect Repair with Anterolateral Thigh Flap in Patients with Oral Squamous Cell Carcinoma/ZHONG Zhaoying.//Medical Innovationof China，2025，22(19)：125-129

    [Abstract]Objective： To explore the effect of Danhong Injection combined with Dexmedetomidine on postoperativedefectrepair with anterolateral thigh flap in patients withoral squamous cellcarcinoma.Method：From January 2022 to May 2O24，96 patients with oral squamous cellcarcinoma who underwent postoperative defect repair with anterolateral thighflapat Ganzhou Cancer Hospital wereselectedastheresearch objects，and they were randomly divided into the observation group (Danhong Injection + Dexmedetomidine + conventional anesthesia， n=48 ) and the control group (conventional anesthesia， n=48 )，the serum vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF)levels，coagulation function，flap survival and recent indicators were compared between two groups.Result： The serum VEGF and bFGF levels intwo groups at 14 d after operation were higher than those before operation ......