利培酮对精神分裂症患者血脂的影响
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【摘要】目的研究利培酮对精神分裂症患者血脂的影响，评价药物的安全性。方法选择88例精神分裂症患者，利培酮治疗4周或8周，观察患者胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)、载脂蛋白A(ApoA)、载脂蛋白B(ApoB)、空腹血糖(Glu)的变化。结果利培酮可引起女性精神分裂症患者血脂TC、TG、HDL、LDL、ApoA、ApoB升高。结论利培酮可引起血脂异常，在治疗精神分裂症时应采取相应的干预措施。
【关键词】利培酮；精神分裂症；血脂
Influence of risperdone for patients with schizophrenia in blood lipid GAN Li-ping.Zhishan Hospital of Yongzhou，Yongzhou 425006，China
【Abstract】ObjectiveTo research the effect of risperidone for patients with schizophrenia in blood lipid and evaluate drug safety.Methods88 patients with schizophrenia had 4 weeks or 8 weeks treatment with risperidone.The patients were observed the difference than before of their cholesterol(TC)，three acylating glycerin(TG)，high-density lipoprotein(HDL)，low-density lipoprotein (LDL)，apolipoprotein A (ApoA)，apolipoprotein B (ApoB)，fasting blood sugar (Glu).ResultsRisperidone can cause lipid TC and TG，HDL，LDL，ApoA，ApoB increase in female patients with schizophrenia.ConclusionRisperidone can cause blood lipid abnormally.It should be taken appropriate interventions in the treatment of schizophrenic ......
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