论文下载：孕妇血型抗体监测在ABO-HDN预防中的意义-新生儿溶血病

孕妇血型抗体监测在ABO-HDN预防中的意义

http://www.100md.com 2011年12月5日吕连华陈勇杨琴

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     【摘要】目的研究孕妇血型IgG抗体效价监测在预防新生儿ABO溶血病(ABO-HDN)中的价值。方法采用改良抗人球蛋白法监测938例O型血孕妇血清IgG抗体效价并对高风险新生儿做ABO-HDN血清学检测。结果孕妇血清抗体效价为1∶64、1∶128和≥1∶256时，新生儿ABO溶血病的发病率分别为1024%、4324%、8947%，不同抗体效价组别间差异有统计学意义。结论孕妇血型抗体效价与ABO-HDN的发病率呈正相关，对ABO-HDN的预防具有重要意义。

    【关键词】孕妇；新生儿溶血病；血型抗体效价

    Maternal blood group antibodies monitoring in prevention of ABO-HDN LV Lian-hua，CHEN Yong，YANG QinThe Peoples Hospital of Mianyang，Mianyang 621000,China

    【Abstract】ObjectiveTo study the value of maternal blood group IgG antibody titer monitoring in prevention of ABO hemolytic disease of newborn (ABO-HDN).MethodsTo monitor sera IgG anti-(A) B antibody 938 cases of pregnant women with blood type O using improved anti-human globulin method and serological detection of hemolytic disease on high-risk newbornsResultsWhen the valence of antibody was 1∶64，1∶128，1∶256 and more,the ABO-HDN incidence rates were 1024%,4324%,8947% respectively.Statistically significants were detected between different antibody titers groupsConclusionThe more the titers of IgG andbody in the sera with pregnant women ......

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