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子宫内膜息肉施行宫腔镜手术治疗的临床观察及患者术后复发预防研究(1)
http://www.100md.com 2019年9月5日 《中外医学研究》 201925
     【摘要】 目的:觀察临床收治子宫内膜息肉患者施行宫腔镜手术治疗的效果及曼月乐与地屈孕酮对术后复发的预防作用。方法:150例研究对象均取自2015年1月-2018年3月笔者所在医院收治子宫内膜息肉患者,均行宫腔镜息肉电切术治疗,以术后所用药物不同分组,比较对照组(地屈孕酮,75例)和观察组(曼月乐,75例)手术情况、月经量及子宫内膜厚度变化情况、随访期疾病复发情况及不良反应情况。结果:两组手术时间、出血量及切除息肉个数比较差异无统计学意义(P>0.05);治疗前两组月经量及子宫内膜厚度比较差异无统计学意义(P>0.05),治疗后观察组各数值均低于对照组(P<0.05);随访期内观察组无复发病例,对照组复发3例,差异无统计学意义(P>0.05);观察组无恶心呕吐等不良反应,对照组发生13例,差异有统计学意义(P<0.05)。结论:针对临床收治子宫内膜息肉病例施行宫腔镜手术治疗有确切疗效,术后应用地屈孕酮及曼月乐均可有效减少术后复发,但曼月乐的应用更为方便,且临床不良反应更少。

    【关键词】 宫腔镜手术; 子宫内膜息肉; 术后复发; 预防; 曼月乐; 地屈孕酮

    doi:10.14033/j.cnki.cfmr.2019.25.020 文献标识码 B 文章编号 1674-6805(2019)25-00-03

    Clinical Observation of Hysteroscopic Surgery for Endometrial Polyps and Prevention of Postoperative Recurrence/YE Yanhong.//Chinese and Foreign Medical Research,2019,17(25):-50

    【Abstract】 Objective:To observe the effect of hysteroscopic surgery in the treatment of endometrial polyps in clinical practice and the preventive effect of Mirena and dydrogesterone on postoperative recurrence.Method:A total of 150 subjects were enrolled in patients with endometrial polyps admitted to our hospital from January 2015 to March 2018.All patients underwent hysteroscopic polypectomy.The patients were divided into two groups according to the postoperative drugs.The operation status,menstrual volume and endometrial thickness changes,the recurrence of the disease during the follow-up period,and the adverse reactions were observed in the observation group(Mirena,75 cases) and the control group(Dydrogesterone,75 cases).Result:There were no significant differences in operation time,blood loss and the number of polyps between the two groups(P>0.05).There were no significant differences in the amount of menstruation and the thickness of the endometrium in the two groups(P>0.05),and the values in the observation group were lower than those of the control group after treatment(P<0.05).There were no recurrence cases in the observation group and 3 cases in the control group during the follow-up period,the difference was not statistically significant(P>0.05).There were no adverse reactions such as nausea and vomiting in the observation group,and 13 cases in the control group,the difference was significant(P<0.05).Conclusion:The application of hysteroscopic surgery for the treatment of endometrial polyps in clinical practice has a definite curative effect.Postoperative application of dydrogesterone and Mirena can effectively reduce postoperative recurrence,but the application of Mirena is more convenient and less clinically adverse., 百拇医药(叶燕红)
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