摘要：目的：比较负压封闭引流术(vacuum sealing drainage，VSD)与传统灌注冲洗术治疗四肢难治性骨感染的疗效。方法：选取2012年1月至2015年1月间我院骨科收治的94例难治性骨感染患者为研究对象，随机分为VSD组和传统组，每组47例；VSD组选用负压封闭引流技术治疗，传统组选用传统灌注冲洗术治疗，对比两组的创面愈合时间、住院时间、治疗费用、治疗有效率。结果：VSD组患者创面愈合时间和住院时间均短于传统组，治疗费用少于传统组，且VSD组的治疗有效率(95.74%)高于传统组(80.85%)，差异均具有统计学意义。结论：VSD的临床疗效优于传统灌注冲洗术，值得在临床上推广。

    关键词：负压封闭引流术；传统灌注冲洗术；难治性骨感染

    Abstract：Objective： To compare the effect of VSD and traditional irrigation technique in the treatment of refractory infection of bone of limbs. Methods： 94 cases of refractory bone infection were as the research object from January 2012 to January 2015 in our hospital. According to the different treatment methods the cases were divided into the VSD group and the traditional group ......