【摘要】目的：分析糖尿病(DM)患者血小板聚集功能和血脂水平的变化情况，探讨两者与心脑血管疾病发病的相关性。方法：应用阻抗法测定血小板聚集功能(PAgT),引用日立7680型全自动生化分析仪测定总胆固醇(TC)、甘油三酯(TG)在不同分组中的含量。结果：糖尿病患者血小板聚集率 (PAgT)、总胆固醇(TC)、甘油三酯(TG)与正常对照组有有明显升高，其差异有统计学意义(p<0.05).结论：测定血小板聚集实验和血浆中血脂水平的变化，对指导糖尿病治疗和预防心脑血管疾病的发生有重要意义。

    【Abstract】Objective To explore the detection and clinical significance of blood platelet aggregation 、TC and TG levels in patients with type 2diabetes mellitus(DM).Methods: PAgT were measured simutaneously using a whole-blood Lumi Aggregometer and TC TG levels were measured using Hitachi 7180 system in 40 health control group and 40 patient with DM (DM group).Result in DM group PAgTTC and TG levels were significantly higher than those of control group . Conclusion There was an abnormal activated plate in patients with type 2 diabetes mellitus ,which may lead coagulationg system presenting and abnormal higher levels.It is important for the diagnosis and therapy of DM observe the change of the PAgTTG and TC .

    糖尿病(diabetes,DM)是由遗传因素、免疫功能紊乱、微生物感染及其毒素等各种致病因子作用于机体导致胰岛素缺乏和(或)胰岛素生物作用障碍而引起的糖、蛋白质、脂肪等一系列代谢紊乱综合征 ......