浅谈如何对中药新药进行筛选
【摘要】目的 探讨中药新药的筛选方法方法 建立现代中药新药筛选系统,利用OLIGo芯片技术,建立动物模型、基因表达差异谱数据库、高速计算机和处方模拟软件,对整体动物药效学试验验证,达到对中药新药有效性的检测。结果新药筛选系统可使中药的理论和作用机制明确,使使中药从根本上实现现代化、国际化。结论新药筛选系统是一个中药研究的有效方法,为中药现代化研究提供了一个全新的思路和方向。
【关键词】中药新药;中药筛选;中药新药筛选系统
How to screening of Chinese herbal medicine
Yan Wu Maternal and Child Health Hospital of Hubei Xuan'en445500
【Abstract】ObjectiveNew drug screening methods of traditional Chinese medicine MethodsEstablishment of a modern Chinese medicine drug screening systems, the use OLIGo chip technology, the establishment of animal models, gene expression differences in spectral databases, high-speed computer and prescription simulation software, on the whole animal pharmacodynamic test verification, to test the effectiveness of Chinese herbal medicine. Results Drug screening system allows the mechanism of traditional Chinese medicine theory and clear, so fundamental to traditional Chinese medicine modernization and internationalization.ConclusionDrug screening system is an effective method of Traditional Chinese Medicine Research, as the modernization of Chinese medicine study provides a new thought and direction. ......
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