脐血铅浓度与新生儿端粒长度的相关性(2)
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[Key words] Umbilical cord blood;Lead;Neonate;Telomere length
Telomere,the outer most ends of the chromosomes,is essential for chromosomal stability and integrity.Telomere
consists of repeats of DNA sequences,and it’s function is to stabilize chromosome to prevent end-to-end fusion between chromosomes,degradation, rearrangement,and chromosome loss.As the normal somatic cell undergoes mitosis constantly,so telomere length shortens correspondingly. When telomere reaches a critical length,it can prevent the further division of the cell ......
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