脐血铅浓度与新生儿端粒长度的相关性(5)
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In addition to genetic factors,telomere length also be affected by environment.Of the environmental factors, lead was the biggest threat to neonatal growth. Lead enters the body through the respiratory tract and is not easily expelled. It can cause a variety of viscera damage to human body.It can affect telomere length extension,cell survival, and interfere with cell function. A study found that long lead exposure can induce telomere length shortening. Some studies also showed that[18]in the lead exposure environment,telomerase activity decreases could influence the regulation of telomere length. Therefore, the change of telomere length in the neonate may be associated with lead exposure ......
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