【摘 要】目的：观察补阳还五汤联合柳氮磺吡啶治疗强直性脊柱炎的临床疗效及安全性。方法：将47例强直性脊柱炎患者随机分为治疗组23例和对照组24例。对照组口服柳氮磺吡啶，治疗组在对照组治疗基础上加用补阳还五汤。两组均治疗6个月，观察两组治疗前后临床评价指标的改善情况，并对不良反应进行评价。结果：治疗后，两组患者的各项临床指标均有明显改善(P < 0.05)，且治疗组改善优于对照组(P < 0.05)，也未出现不良反应。结论：补阳还五汤联合柳氮磺吡啶治疗强直性脊柱炎安全有效，值得推广应用。

    【关键词】 脊柱炎，强直性；补阳还五汤；柳氮磺吡啶

    doi：10.3969/j.issn.2095-4174.2015.03.003

    【ABSTRACT】 Objective： To observe the clinical efficacy and safety of Buyang Huanwu Decoction combining sulfasalazine in the treatment of ankylosing spondylitis.Methods： 47 cases of ankylosing spondylitis were randomly divided into a treatment group(23 cases) and a control group(24 cases) according to the admission time.The control group was orally given sulfasalazine ......