王彦鹏 张银珍 莫易方

    【摘 要】目的：分析原发性骨质疏松症的相关文献，进一步明确骨质疏松症危险因素的研究状况及发展趋势。方法：计算机检索中国知网、万方、维普等数据库中有关原发性骨质疏松症危险因素的北京大学中文核心期刊目录所收录的文献，对基本信息及相关危险因素进行统计。结果：共纳入79篇文献，仅有1篇文献为多中心研究，其余均为单个地区的研究。原发性骨质疏松症相关危险因素中，以年龄、体质量指数(BMI)、吸烟、性别、女性绝经状况等因素出现的频数最高。饮酒、饮茶等因素是否为原发性骨质疏松症的危险因素尚存在分歧。结论：年龄、BMI、吸烟、性别、女性绝经状况作为原发性骨质疏松症的危险因素已达成共识，而饮酒、饮茶等相关因素是否为原发性骨质疏松症的危险因素仍存在一定争议，今后应针对性开展多中心研究。

    【关键词】 原发性骨质疏松症;危险因素;保护因素;骨密度;文献研究

    【ABSTRACT】Objective：To analyze the literature related to primary osteoporosis and further clarify the research status and development trend of risk factors of osteoporosis.Methods：The literature included in the catalogue of Chinese Core Journals of Peking University on risk factors of primary osteoporosis in databases such as CNKI，VIP and Wanfang were searched by computer，and the basic information and related risk factors were counted.Results：A total of 79 literature were included ......