甲巯咪唑和丙硫氧嘧啶治疗甲亢不良反应临床思路刍议
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【摘要】分析研究甲巯咪唑和丙硫氧嘧啶治疗甲亢的不良反应，为临床治疗甲亢提供经验。方法：选取本院2012年2月—2014年2月期间收治的30例甲亢患者，对他们的资料进行回顾性分析。将他们随机分为甲巯咪唑组和丙硫氧嘧啶组，每组各15人，分别采用两种药物对比分析产生的不良反应。结果：甲巯咪唑组的皮疹、红细胞、白细胞和血小板与丙硫氧嘧啶组都有所减少，P<0.05。肝功能损坏方面，丙硫氧嘧啶组的损坏情况要比甲巯咪唑组严重(P<0.05)。结论：两种药物对于治疗甲亢都会产生不良反应，在临床使用中要酌情使用。
【关键词】甲巯咪唑丙硫氧嘧啶不良反应甲亢临床肝功能
【Abstract】Objective: to analyze the adverse drug reactions of methimazole and propylthiouracil treatment of hyperthyroidism, provide experience for the clinical treatment of hyperthyroidism. Methods: 30 patients in our hospital from 2012 February to 2014 February period were treated, their data were analyzed retrospectively. They were randomly divided into methimazole and propylthiouracil group group, each group of each 15 people, compared with two kinds of drug adverse reactions of the. Results: methimazole group rash, red cells, white cells and platelets and propylthiouracil group were decreased, P< 0.05. Liver function damage, the damage is more serious than propylthiouracil group methimazole group (P< 0.05). Conclusion: the two drugs for the treatment of hyperthyroidism will produce adverse reactions, should use discretion in clinical use. ......
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