青藏高原地区老年人衰弱指数与睡眠监测指标的相关性分析(1)

http://www.100md.com 2018年3月1日 《世界睡眠医学杂志》 20183

     摘要目的：探討青藏高原地区老年人睡眠监测指标与衰弱情况之间的关系。方法：以衰弱指数量表调查结合标准多导睡眠监测情况。对青海红十字医院老年科住院体检的63～93岁(805)老人29名体检情况进行分析。结果：血红蛋白、衰弱等级、REM潜伏期在80岁以下组及80岁以上(包括80岁)两个年龄组间差异有统计学意义(P<005)；平均红细胞体积与TOTAL氧减指数在不同程度的OSAHS组(AHI1499正常，5～1499轻度，15～2999中度，30以上重度)间差异有统计学意义(P<005)；衰弱指数与睡眠监测指标的相关性分析显示：衰弱指数与年龄呈正相关(r=0495)，与血红蛋白呈负相关(r=-0473)、与白蛋白呈负相关(r=-0626)，相关性有统计学意义(P<001)；与REM潜伏期呈正相关(r=0381)，与总胆固醇呈负相关(r=-0395)、与高密度脂蛋白呈负相关(r=-0412)，相关性有统计学意义(P<005)。AHI指数与睡眠监测指标的相关性分析显示：AHI指数与TOTAL氧减指数呈正相关(r=0964)、与高密度脂蛋白呈正相关(r=0533)，相关性有统计学意义(P<001)；与白蛋白呈正相关(r=0449)、与白球比呈正相关(r=0380)、与血糖呈正相关(r=0416)，相关性有统计学意义(P<005)。结论：衰弱指数与年龄、REM潜伏期、血红蛋白、白蛋白、总胆固醇、高密度脂蛋白之间具有相关性。AHI指数与TOTAL氧减指数、高密度脂蛋白、白蛋白、白球比、血糖之间具有相关性。

    关键词老年；衰弱指数；睡眠呼吸暂停；相关性分析

    中图分类号：R592文献标识码：Adoi：103969/jissn2095-7130201803006

    Correlation Analysis Between Frailty Index and Sleep Monitoring Index

    of the Elderly in Qinghai Tibet Plateau Region

    Yang Baoliang1，Chen Yongxin2，Ma Jianlin2，Chen Zhenguo1，Duan Chengmin1，Feng Lei1，An Jing1，Liu Peng1，3，Peng Kangkang1，3，Hao Lijuan1

    (1Department of Sleep Medicine，Qinghai Red Cross Hospitai，Xining，810000； 2Department of Geriatrics，Qinghai Red Cross Hospitai，Xining，810000； 3Qinghai University，Xining，810001)

    AbstractObjective：To discuss on relevance between sleep monitoring index of the elderly and frailty situation in Qinghai Tibet Plateau Region. Methods：Physical examination situation of 29 old patients aged from 63 to 93 years old(805)who took physical examination in 20162017 in geriatrics department of Qinghai Red Cross Hospital was analyzed，which was conducted by frailty index scale combined with standard polysomnography monitoring situation. Results：There was statistical significance(P<005)between group of under 80 years old and above 80 years old(including 80)in hemoglobin，frailty levels and ncubation period of rapid eyes movement.There was statistical significance(P<005)between mean corpuscular volume and TOTAL oxygen desaturation index of obstructive sleep apneahypopnea syndrome group with different concentrations(AHI1～499 normal，5～1499 mild，15～2999 moderate，and no less than 30 severe). Conclusion：Analysis between frailty index and sleep monitoring index indicated that，frailty index has positive correlation to age(r=0495)，negatively correlated to hemoglobin(r=-0473)，negatively correlated to albumin(r=-0626)，with statistical significance(P<001)； it had positive correlation to incubation period of rapid eyes movement(r=0381)，negative correlation to total cholesterol(r=-0395)，negatively correlated to high density lipoprotein(r=-0412)，with statistical significance(P<005)； correlation analysis between apnea hypopnea index and sleep monitoring index indicated that AHI index had positive correlation to TOTAL oxygen reduction index(r=0964)，negatively correlated to high density lipoprotein(r=0533)，with statistical significance(P<001)； it had positively associated to albumin(r=0449)，positively correlated to white sphere ratio(r=0380)，and positive correlation to blood glucose(r=0416)，with statistical significance(P<005). Conclusion：Frailty index had correlation with age，REM latency，hemoglobin，albumin，total cholesterol，and highdensity lipoproteinAHI index had correlation with TOTAL oxygen reduction index，high density lipoprotein，albumin，white ball ratio，blood glucose.(杨宝良 陈永新 马建林 陈振国 段成民 冯磊 安静 刘鹏 彭康康 郝丽娟)

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