黛力新辅助治疗胃食管反流病的临床效果及对睡眠的影响(1)

http://www.100md.com 2018年7月1日 《世界睡眠医学杂志》 20187

     摘要目的：探析黛力新輔助治疗胃食管反流病及对其睡眠质量的影响。方法：选取2015年12月至2017年12月广西钦州市第二人民医院收治的胃食管反流病患者124例，按照随机分配的原则分为观察组和对照组，每组62例。给予对照组常规药物治疗，观察组在对照组基础上增加黛力新治疗，比较分析2组的治疗效果。结果：观察组的治疗有效率为9677%，明显高于对照组的8710%，2组比较，差异有统计学意义(P<005)；经治疗后，2组患者的焦虑、抑郁情绪较治疗前均明显改善，且观察组明显优于对照组，差异有统计学意义(P<005)；治疗后，2组患者的PSQI评分明显低于治疗前，且观察组优于对照组。2组比较，差异有统计学意义(P<005)；2组患者治疗期间的不良反应发生率比较，差异无统计学意义(P>005)。结论：黛力新辅助治疗胃食管反流病的临床效果显著，可改善患者的负面情绪，提升患者的睡眠质量，且安全性较高，故值得在临床上推广和应用。

    关键词黛力新；胃食管反流病；睡眠质量；治疗效果

    中图分类号：R573文献标识码：Adoi：103969/jissn2095-7130201807009

    Clinical Effect of Deanxit in the Treatment of Gastroesophageal

    Reflux Disease and its Effect on Sleep

    Huang Qiao

    (Department of Gastroenterology，Qinzhou Second People′s Hospital，Qinzhou，535000)

    AbstractObjective：To explore the effect of Deanxit in the treatment of patients with gastroesophageal reflux disease and its influence on sleep qualityMethods：A tatal of 120 patients with gastroesophageal reflux disease who were treated in Qinzhou Second People′s Hospital from December 2015 to December 2017 were selected as the study subjects and the patients were randomly divided into observation group and control group，62 cases in each groupThe control group was given conventional drug treatment，while the observation group was treated with Deanxit on the basis of the control groupThe therapeutic effects of the 2 groups were compared and analyzedResults：The effective rate of observation in the observation group was 9677%，which was significantly higher than that in the control group(8710%)There was a significant difference between the two groups(P<005)After treatment，the anxiety and depression of the observation group were significantly improved compared with those before treatment，And significantly better than the control group，the difference was statistically significant(P<005)； after treatment，the patients in the observation group PSQI score was significantly better than before treatment and the control group，the difference between the two groups was statistically significant(P<005). There was no significant difference in the incidence of adverse reactions during treatment between the two groups(P>005)Conclusion：The new clinically effective treatment of gastroesophageal reflux disease is significantly effectiveIt can improve the patient′s negative emotions，improve the quality of sleep of patients，and has high safetyIt is worthy of promotion and application in clinical practice.

    Key WordsDeanxit； Gastroesophageal reflux disease； Sleep quality； Therapeutic effect(黄乔)

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