多毛症与非多毛症多囊卵巢综合征妇女基线特征与临床结局(3)
4 結论
尽管我国人群PCOS多毛症发生率并不高，但仍会严重影响患者生存生命质量，应引起足够重视。本研究发现PCOS多毛症患者具有较低受孕率的临床结局特点，然而仍需大样本随机对照临床试验进一步证实。
参考文献
[1]Wu X K，Wang Y Y，Liu J P，et al.Randomized controlled trial of letrozole，berberine，or a combination for infertility in the polycystic ovary syndrome[J].Fertility & Sterility，2016，106(3)：757-765.e1.
[2]Keen M A，Shah I H，Sheikh G.Cutaneous Manifestations of Polycystic Ovary Syndrome：A Cross-Sectional Clinical Study[J].2017，8(2)：104-110.
, http://www.100md.com
[3]Khomami M B，Tehrani F R，Hashemi S，et al.Of PCOS Symptoms，Hirsutism Has the Most Significant Impact on the Quality of Life of Iranian Women[J].Plos One，2015，10(4)：e0123608.
[4]Ehrmann D A，Liljenquist D R，Kasza K，et al.Prevalence and predictors of the metabolic syndrome in women with polycystic ovary syndrome[J].J Clin Endocrinol Metab，2006，91(1)：48-53.
[5]Group E S P C W.Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome[J].Fertility & Sterility，2004，81(1)：19-25.
, 百拇医药
[6]Yan L，Kuang H，Shen W，et al.Letrozole，berberine，or their combination for anovulatory infertility in women with polycystic ovary syndrome：study design of a double-blind randomised controlled trial[J].Bmj Open，2013，3(11)：e003934.
[7]Irving F S M D，Michael L L M D.Amenorrhea associated with bilateral polycystic ovaries[J].American Journal of Obstetrics & Gynecology，1935，29.
[8]Burns T，Breathnach S，Cox N，et al.Rook′s Textbook of Dermatology，Eighth Edition[M].2010.
, http://www.100md.com
[9]Homburg R.Antiandrogens in gynaecology：an overview[J].Gynaecology Forum，2001.
[10]郝淑贤，于秋晓，宋茜，等.多囊卵巢综合征并发抑郁症的研究现状[J].生理科学进展，2017，48(4)：257-263.
[11]Pavii'c B D，krgati'c L，Bukvi'c M Z，et al.Hyperandrogenemia association with acne and hirsutism severity in Croatian women with polycystic ovary syndrome[J].Acta Dermatovenerologica Croatica Adc，2013，21(2)：105.
[12]Chang W Y，Knochenhauer E S，Bartolucci A A，et al.Phenotypic spectrum of polycystic ovary syndrome：clinical and biochemical characterization of the three major clinical subgroups[J].Fertility & Sterility，2005，83(6)：1717-1723.
, 百拇医药
[13]Azziz R，Woods K S，Reyna R，et al.The Prevalence and Features of the Polycystic Ovary Syndrome in an Unselected Population[J].J Clin Endocrinol Metab，2004，89(6)：2745-2749.
[14]Yuan C，Liu X，Mao Y，et al.Polycystic ovary syndrome patients with high BMI tend to have functional disorders of androgen excess：a prospective study[J].Journal of Biomedical Research，2016，30(3)：197-202., 百拇医药(高敬书 何慧 王宇 吴效科)
尽管我国人群PCOS多毛症发生率并不高，但仍会严重影响患者生存生命质量，应引起足够重视。本研究发现PCOS多毛症患者具有较低受孕率的临床结局特点，然而仍需大样本随机对照临床试验进一步证实。
参考文献
[1]Wu X K，Wang Y Y，Liu J P，et al.Randomized controlled trial of letrozole，berberine，or a combination for infertility in the polycystic ovary syndrome[J].Fertility & Sterility，2016，106(3)：757-765.e1.
[2]Keen M A，Shah I H，Sheikh G.Cutaneous Manifestations of Polycystic Ovary Syndrome：A Cross-Sectional Clinical Study[J].2017，8(2)：104-110.
, http://www.100md.com
[3]Khomami M B，Tehrani F R，Hashemi S，et al.Of PCOS Symptoms，Hirsutism Has the Most Significant Impact on the Quality of Life of Iranian Women[J].Plos One，2015，10(4)：e0123608.
[4]Ehrmann D A，Liljenquist D R，Kasza K，et al.Prevalence and predictors of the metabolic syndrome in women with polycystic ovary syndrome[J].J Clin Endocrinol Metab，2006，91(1)：48-53.
[5]Group E S P C W.Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome[J].Fertility & Sterility，2004，81(1)：19-25.
, 百拇医药
[6]Yan L，Kuang H，Shen W，et al.Letrozole，berberine，or their combination for anovulatory infertility in women with polycystic ovary syndrome：study design of a double-blind randomised controlled trial[J].Bmj Open，2013，3(11)：e003934.
[7]Irving F S M D，Michael L L M D.Amenorrhea associated with bilateral polycystic ovaries[J].American Journal of Obstetrics & Gynecology，1935，29.
[8]Burns T，Breathnach S，Cox N，et al.Rook′s Textbook of Dermatology，Eighth Edition[M].2010.
, http://www.100md.com
[9]Homburg R.Antiandrogens in gynaecology：an overview[J].Gynaecology Forum，2001.
[10]郝淑贤，于秋晓，宋茜，等.多囊卵巢综合征并发抑郁症的研究现状[J].生理科学进展，2017，48(4)：257-263.
[11]Pavii'c B D，krgati'c L，Bukvi'c M Z，et al.Hyperandrogenemia association with acne and hirsutism severity in Croatian women with polycystic ovary syndrome[J].Acta Dermatovenerologica Croatica Adc，2013，21(2)：105.
[12]Chang W Y，Knochenhauer E S，Bartolucci A A，et al.Phenotypic spectrum of polycystic ovary syndrome：clinical and biochemical characterization of the three major clinical subgroups[J].Fertility & Sterility，2005，83(6)：1717-1723.
, 百拇医药
[13]Azziz R，Woods K S，Reyna R，et al.The Prevalence and Features of the Polycystic Ovary Syndrome in an Unselected Population[J].J Clin Endocrinol Metab，2004，89(6)：2745-2749.
[14]Yuan C，Liu X，Mao Y，et al.Polycystic ovary syndrome patients with high BMI tend to have functional disorders of androgen excess：a prospective study[J].Journal of Biomedical Research，2016，30(3)：197-202., 百拇医药(高敬书 何慧 王宇 吴效科)